GAMT Antibody

• Catalog number
  bs-13278R
• Price
  Please ask
• Size
  0.1ml

• Long name
  GAMT Primary Polyclonal Antibody
• Also known as
  GAMT PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  GAMT
• Specificity
  This is a highly specific antibody against GAMT.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  150-200/236
• Subcellular location
  Cytoplasm
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human GAMT
• Gene ID number
  2593
• Swiss Prot
  Q14353
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  In the creatine biosynthesis pathway, glycine is converted to guanidinoacetate by amidinotransferase, and guanidinoacetate is then converted to creatine by Guanidinoacetate N-methyltransferase (GAMT). GAMT, a methyltransferase, uses S-adenosylmethionine as the methyl donor for this reaction. Methyltransferases are a type of transferase enzyme which transfers a methyl group to nucleic bases in DNA or amino acids in protein. Encoding a 236 amino acid protein, the human GAMT gene maps to chromosome 19p13.3. Defects in the GAMT gene leads to GAMT deficiency, which is associated with guanidinoacetate accumulation and decreased levels of creatine excretion in brain. Such biochemical changes are thought to lead to various neurological syndromes and muscular hypotonia.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  PIG2; CCDS2; TP53I2; HEL-S-20; Guanidinoacetate N-methyltransferase; GAMT
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  GAMT  
• Gene symbol
  GAMT
• Short name
  Anti-GAMT
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  GAMT Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:4136
• Gene
  GAMT
• Long gene name
  guanidinoacetate N-methyltransferase
• Synonyms
  • PIG2
  • TP53I2
• GenBank acession
  • Z49878
• Locus
  19p13.3
• Discovery year
  1996-07-19
• Entrez gene record
  2593
• Pubmed identfication
  • 9570966
  • 8547310
• RefSeq identity
  • NM_138924
• Classification
  • 7BS small molecule methyltransferases
• VEGA ID
  OTTHUMG00000180095
• Locus Specific Databases
  • Global Variome shared LOVD

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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