Gambogic acid for cell activation

Gambogic acid for cell activation is available 2 times from Biovision labs

2785-5 | Gambogic acid for cell activationsize: 5 mg | 202.79 USD

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2785-25 | Gambogic acid for cell activationsize: 25 mg | 631.55 USD

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  • Description
    Gambogic acid is a plant-derived natural product that acts as a caspase activator and apoptosis inducer, which causes an irreversible arrest in the G2/M phase of the cell cycle. It causes a decrease of Bcl-2 gene and an increase in Bax gene expression, which may result in apoptosis. Gambogic also acts as an inhibitor of A1 and Bcl-2 family proteins, including Bcl-xl, Bcl-2, Bcl-w, Bcl-B, Bfl-1, and Mcl-1.
  • Peptide sequence
    N/A
  • CAS number
    2752-65-0
  • Molecular weight
    628.75
  • Category
    Biochemicals
  • Other name
     (Z)-4-((1S,3aR,5S,11R,14aS)-8-hydroxy-2,2,11-trimethyl-13-(3-methylbut-2-en-1-yl)-11-(4-methylpent-3-en-1-yl)-4,7-dioxo-2,3a,4,5,7,11-hexahydro-1H-1,5-methanofuro[3,2-g]pyrano[3,2-b]xanthen-3a-yl)-2-methylbut-2-enoic acid
  • Molecular formula
    C₃₈H₄₄O₈
  • Physical appearance
    Orange solid
  • Supplied with
    N/A
  • Is this a salt?
    No
  • Is it cell-permeable?
    Y
  • Purification
    ≥95%
  • Reconstitute instructions
    DMSO (>25 mg/ml) or EtOH (~20 mg/ml)
  • Storage condition
    -20°C
  • Shipping condition
    Gel Pack
  • Maximum time for storage
    36 months
  • Storage instructions
    Protect from air and light
  • Additional description
    For cells, cell lines and tissues in culture till half confluency.
  • Gene target
  • Short name
    Gambogic acid for activation
  • Technique
    activation
  • Alternative name
    Gambogic acid to measure cellular activation
  • Tissue
    cell
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