FBXL21 Polyclonal Antibody

• Catalog number
  CAC07687
• Price
  Please ask
• Size
  100 μg

• Other name
  F-box/LRR-repeat protein 21,F-box and leucine-rich repeat protein 21,F-box and leucine-rich repeat protein 3B,F-box/LRR-repeat protein 3B,FBXL21,FBL21,FBL3,FBXL3B,FBXL3P
• Immunogen
  Recombinant human F-box/LRR-repeat protein 21 protein (78-137AA)
• Verified reactivity
  Human, Mouse
• Verified applications
  ELISA,WB,IHC,IF
• Raised in
  Rabbit
• Clonality
  Polyclonal
• Protein number
  Q9UKT6
• Gene number
  Please refer to GenBank
• NCBI number
  Please refer to NCBI
• Purity
  Protein G purified, >95%
• Storage recommendation
  Aliquot and store at -20°C. Minimize freezing and thawing.
• Use before
  1 year
• Shipping requirements
  Blue ice
• Estimated production time
  3-7 business days
• Supplementary information
  Substrate-recognition component of the SCF(FBXL21) E3 ubiquitin ligase complex involved in circadian rhythm function. Plays a key role in the maintenance of both the speed and the robustness of the circadian clock oscillation. The SCF(FBXL21) complex mainly acts in the cytosol and mediates ubiquitination of CRY proteins (CRY1 and CRY2), leading to CRY proteins stabilization. The SCF(FBXL21) complex counteracts the activity of the SCF(FBXL3) complex and protects CRY proteins from degradation. Involved in the hypothalamic suprachiasmatic nucleus (SCN) clock regulating temporal organization of the daily activities (By similarity).
• Notes
  For research use only. Not for diagnostic procedures.
• Hyperlink
• Properties
  If you buy Antibodies supplied by bioma they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Group
  Polyclonals and antibodies
• About
  Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
• French translation
  anticorps

• Gene target
  FBXL21  
• Gene symbol
  FBXL21P
• Short name
  FBXL21 Polyclonal Antibody
• Technique
  Polyclonal, Antibody, antibodies against human proteins, antibodies for, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
• Label
  Unconjugated
• Alternative name
  FBXL21 polyclonal (antibody to-)
• Alternative technique
  polyclonals, antibodies

Gene info

• Identity
  HGNC:13600
• Gene
  FBXL21P
• Long gene name
  F-box and leucine rich repeat protein 21, pseudogene
• Synonyms gene
  • FBXL3B
  • FBXL3P
  • FBXL21
• Synonyms gene name
  • F-box and leucine-rich repeat protein 3 pseudogene
  • F-box and leucine-rich repeat protein 21
  • F-box and leucine rich repeat protein 21 (gene/pseudogene)
• Synonyms
  • FBL3B
  • Fbl21
• GenBank acession
  • AF129533
• Locus
  5q31.1
• Discovery year
  2000-09-27
• Entrez gene record
  26223
• Pubmed identfication
  • 10531035
• RefSeq identity
  • NR_152420
• Classification
  • F-box and leucine rich repeat proteins
• VEGA ID
  OTTHUMG00000155971

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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