Factor XIIIa Activity Assay Kit (Colorimetric)

• Catalog number
  K522-100
• Price
  Please ask
• Size
  100 assays

• Summary
  • Detection method- Colorimetric (Absorbance 340 nm) • Applications- Measurement of FXIIIa activity in plasma and purified/crude enzyme preparations
• Detection Method
  Detection method- Colorimetric (Absorbance 340 nm)
• Applications
  Measurement of Factor XIIIa activity in plasma samples and purified/crude enzyme preparations
• Sample Type
  • Adherent and suspension cell lysates • Animal tissues such as rat liver • Purified enzyme
• Features Benefits
  • Simple, rapid & convenient assay to measure Factor XIIIa • Includes Positive Control and Inhibitor (Iodoacetamide)
• Storage Conditions
  -20°C
• Shipping Conditions
  gel pack
• Shelf life
  12 months
• Background
  Factor XIII or fibrin stabilizing factor (EC 2.3.2.13) is an enzyme involved in the blood coagulation system that crosslinks fibrin. Factor XIII is a transglutaminase that circulates in the plasma as a heterotetramer of two catalytic “A” subunits and two carrier “B” subunits. Factor XIII is activated by thrombin in the presence of calcium which leads to the release of the activation peptide, followed by the dissociation of carrier subunits. The activated Factor XIII (XIIIa) acts on fibrin (Factor Ia) to form γ-glutamyl-Є-lysyl amide cross links between fibrin molecules leading to the formation of an insoluble clot. The deficiency of Factor XIII affects fibrin clot stability and bleeding disorders. BioVision's Factor XIIIa activity assay kit utilizes the transglutaminase activity of factor XIIIa to cross link an amine-containing substrate to glutamine-containing substrate resulting in the loss of ammonia which can be quantitatively measured by a colorimetric assay. The kit is easy-to-use and can detect Factor XIIIa (as low as 0.1 Loewy U) from plasma and purified protein samples.
• Data Sheet Link
• Test
  Biovision supplies other types of Assays as 1.
• Properties
  Colorimetric assays or detection use UV absorption or enzymatic color reaction.
• Additional description
  Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells.

• Gene target
  Factor   XIIIa   Activity   Kit  
• Short name
  Factor XIIIa Activity Assay Kit (Colorimetric)
• Technique
  colorimetric, Assay, assays, colorimetry
• Host
  Assay
• Alternative name
  Factor XIIIa Activity test reagent (colorimetry)
• Alternative technique
  assays, arrays, kits
• Alternative to gene target
  v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog, C-Kit and CD117 and PBT and SCFR, KIT and IDBG-18980 and ENSG00000157404 and 3815, transferase activity, Extracellular, Kit and IDBG-172083 and ENSMUSG00000005672 and 16590, KIT and IDBG-642326 and ENSBTAG00000002699 and 280832

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