LLGL1 + LLGL2(Ser650+Ser654) Antibody, ALEXA FLUOR 488
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Catalog numberbs-6070R-A488
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Price:
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Size100ul
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Long nameLLGL1 + LLGL2(Ser650+Ser654) Antibody, ALEXA FLUOR 488 Conjugated
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Also known asAnti-LLGL1 + LLGL2 Ser650+Ser654 PAb ALEXA FLUOR 488
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CategoryConjugated Primary Antibodies
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Conjugated withALEXA FLUOR® 488
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Host OrganismRabbit (Oryctolagus cuniculus)
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Target AntigenLLGL1 + LLGL2 Ser650+Ser654
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SpecificityThis is a highly specific antibody against LLGL1 + LLGL2 Ser650+Ser654.
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ModificationPhosphorylation
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Modification SiteSer650+Ser654
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ClonalityPolyclonal
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ClonePolyclonal antibody
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Concentration1ug per 1ul
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SourceKLH conjugated synthetic phosphopeptide derived from mouse LLGL1 around the phosphorylation site of Ser650+Ser654
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Gene ID Number3996
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Tested applicationsIF(IHC-P)
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Recommended dilutionsIF(IHC-P)(1:50-200)
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CrossreactivityHuman, Mouse, Rat
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Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the antigenLLGL1 is a protein that is similar to a tumor suppressor in Drosophila. The protein is part of a cytoskeletal network and is associated with nonmuscle myosin II heavy chain and a kinase that specifically phosphorylates this protein at serine residues. The gene for LLGL1 is located within the Smith-Magenis syndrome region on chromosome 17. LLGL2 is a protein similar to lethal giant larvae of Drosophila. In fly, the protein's ability to localize cell fate determinants is regulated by the atypical protein kinase C (aPKC). In human, this protein interacts with aPKC-containing complexes and is cortically localized in mitotic cells.
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PurificationPurified by Protein A.
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Storage conditionsStore this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
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Excitation emission499nm/519nm
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SynonymsLLGL1 + LLGL2 phospho S650 + S654; LLGL1 + LLGL2 phospho Ser650 + Ser654; p-LLGL1 + p-LLGL2 S650 + S654; p-LLGL1/LLGL2 Ser650 + Ser654; p-LLGL1/LLGL2 S650 + S654; p-LLGL1/LLGL2 Ser650/654; DLG4; HGL; HUGL; HUGL1; lethal giant larvae homolog 1; lethal giant larvae homolog 2; Lethal2 giant larvae protein homolog 1; Lethal2 giant larvae protein homolog 2; LGL2; LLGL; L2GL1_HUMAN; L2GL2_HUMAN.
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PropertiesFor facs or microscopy Alexa 1 conjugate. Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), yet the Anti-LLGL1 + LLGL2 Ser650+Ser654 has a very high photo stability. As a result of this photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry. It is distinguished in the FL1 of a FACS-Calibur or FACScan. Also Alexa Fluor 488 is pH stable. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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ConjugationAlexa Fluor
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French translationanticorps
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Gene target
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Gene symbolLLGL2, LLGL1
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Short nameAnti-LLGL1 + LLGL2 Ser650+Ser654
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TechniqueAntibody, antibodies against human proteins, antibodies for
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IsotypeImmunoglobulin G (IgG)
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LabelALEXA FLUOR 488
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Alternative nameLLGL1 + LLGL2(Ser650+Ser654) Antibody, ALEXA FLUOR 488
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Alternative techniqueantibodies
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Alternative to gene targetlethal giant larvae homolog 1 (Drosophila), DLG4 and HUGL and HUGL-1 and HUGL1 and LLGL, LLGL1 and IDBG-33645 and ENSG00000131899 and 3996, protein kinase binding, Cytoplasm, Llgl1 and IDBG-181336 and ENSMUSG00000020536 and 16897, LLGL1 and IDBG-638036 and ENSBTAG00000004635 and 781865
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Gene info
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Identity
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Gene
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Long gene nameLLGL scribble cell polarity complex component 2
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Synonyms gene name
- lethal giant larvae homolog 2 (Drosophila)
- lethal giant larvae homolog 2, scribble cell polarity complex component
- LLGL2, scribble cell polarity complex component
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Synonyms
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GenBank acession
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Locus
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Discovery year1997-01-28
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- WD repeat domain containing
- Scribble complex
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameLLGL scribble cell polarity complex component 1
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Synonyms gene
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Synonyms gene name
- lethal giant larvae homolog 1 (Drosophila)
- lethal giant larvae homolog 1, scribble cell polarity complex component
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Synonyms
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Locus
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Discovery year1995-09-12
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Entrez gene record
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Pubmed identfication
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Classification
- Scribble complex
- WD repeat domain containing
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data