EBF2 Antibody

• Catalog number
  bs-11740R
• Price
  Please ask
• Size
  0.1ml

• Long name
  EBF2 Primary Polyclonal Antibody
• Also known as
  EBF2 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  EBF2
• Specificity
  This is a highly specific antibody against EBF2.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human EBF2
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Early B-cell factor 2 is a 575 amino acid protein belonging to the COE family of proteins, whose members are all helix-loop-helix transcription factors. EBF2 is a transcription factor which, in synergy with the Wnt-responsive LEF1/CTNNB1 pathway, activates the decoy receptor for RANKL, OPG, in osteoblasts. OPG, in turn, regulates osteoclast differentiation. Lack of EBF2 has been found to cause a small defect in the terminal differentiation of osteoblasts, along with reduced bone mass and an increase in osteoclasts. Localized to the nucleus, EBF2 forms a homodimer or a heterodimer with a related family member.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  COE 2; COE2; Collier Olf and EBF 2; Early B cell factor 2; EBF 2; FLJ11500; Metencephalon mesencephalnon olfactory transcription factor 1; O/E 3; O/E3; OE 3; OE3; OLF 1/EBF like 3; Transcription factor COE2; COE2_HUMAN.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  EBF2  
• Gene symbol
  EBF2
• Short name
  Anti-EBF2
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  EBF2 Polyclonal Antibody
• Alternative technique
  antibodies
• Alternative to gene target
  early B-cell factor 2, EBF2 and IDBG-281524 and ENSG00000221818 and 64641, protein dimerization activity, nuclei, Ebf2 and IDBG-175890 and ENSMUSG00000022053 and 13592, BT.59602 and IDBG-635598 and ENSBTAG00000040390 and

Gene info

• Identity
  HGNC:19090
• Gene
  EBF2
• Long gene name
  EBF transcription factor 2
• Synonyms gene name
  • early B cell factor 2
• Synonyms
  • FLJ11500
  • COE2
• Synonyms name
  • Collier, Olf and EBF transcription factor 2
• GenBank acession
  • AK021562
  • AK001144
• Locus
  8p21.2
• Discovery year
  2002-08-09
• Entrez gene record
  64641
• Pubmed identfication
  • 9151732
• RefSeq identity
  • NM_022659
• Classification
  • Early B-cell factors
  • IPT domain containing
• VEGA ID
  OTTHUMG00000163838

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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