E4F1 Antibody

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• Catalog number
  bs-9724R
• Price:

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• Size
  0.1ml

# #

• Long name
  E4F1 Primary Polyclonal Antibody
• Also known as
  E4F1 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  E4F1
• Specificity
  This is a highly specific antibody against E4F1.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human E4F1
• Gene ID number
  1877
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  E4F1, also known as E4F, is a 784 amino acid protein that localizes to both the nucleus and the cytoplasm and contains nine C2H2-type zinc fingers. Expressed ubiquitously in adult and fetal tissues, E4F1 exists as a homodimer that binds DNA and is thought to act as a transcriptional repressor and may also play a role in cell survival and growth via cell cycle control. Additionally, E4F1 is thought to function as a ubiquitin ligase that mediates the ubiquitination (and subsequent degradation) of target proteins and may be involved in the p53 tumor suppressor pathway. E4F1, which may be post-translationally phosphorylated or sumoylated, is subject to proteolytic cleavage which results in the creation of a short peptide with specific DNA binding capabilities.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  E4F; E4F transcription factor 1, isoform CRA_b; P120E4F transcription factor; E4F1_HUMAN.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

#

• Gene target
  E4F1  
• Gene symbol
  E4F1
• Short name
  Anti-E4F1
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  E4F1 Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:3121
• Gene
  E4F1
• Long gene name
  E4F transcription factor 1
• Synonyms
  • E4F
• GenBank acession
  • U87269
• Locus
  16p13.3
• Discovery year
  1996-04-12
• Entrez gene record
  1877
• Pubmed identfication
  • 8828041
  • 9530632
  • 9763670
• RefSeq identity
  • NM_004424
• Classification
  • Zinc fingers C2H2-type
• VEGA ID
  OTTHUMG00000177084

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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