Deltex 1 Antibody
-
Catalog numberbs-0399R
-
PricePlease ask
-
Size0.1ml
-
-
Long nameDeltex 1 Primary Polyclonal Antibody
-
Also known asDeltex 1 PAb
-
CategoryPrimary Antibodies
-
ConjugationUnconjugated
-
Target AntigenDeltex 1
-
SpecificityThis is a highly specific antibody against Deltex 1.
-
Modification sNone
-
Modification site sUnmodified antibody
-
ClonalityPolyclonal antibody
-
Clone numberPolyclonal antibody
-
Concentration1ug per 1ul
-
Immunogen range370-420/620
-
Subcellular locationCytoplasm, Nucleus
-
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Deltex-1
-
Gene ID number1840
-
Swiss ProtQ86Y01
-
Tested ApplicationsWB, IHC-P, IF(IHC-P)
-
Recommended dilutionsWB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
-
Cross reactivityHuman, Mouse, Rat
-
Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
-
Background of the target antigenFunctions as a ubiquitin ligase protein in vivo, mediating ubiquitination and promoting degradation of MEKK1, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity (By similarity). Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Mainly acts as a positive regulator of Notch, but it also acts as a negative regulator, depending on the developmental and cell context. Mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. Involved in neurogenesis, lymphogenesis and myogenesis, and may also be involved in MZB (Marginal zone B) cell differentiation. Promotes B-cell development at the expense of T-cell development, suggesting that it can antagonize NOTCH1.
-
Purification methodThis antibody was purified via Protein A.
-
Storage conditionsKeep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
-
Synonym nameshDx-1; E3 ubiquitin-protein ligase DTX1; Protein deltex-1; Deltex1; hDTX1; DTX1
-
PropertiesIf you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
French translationanticorps
-
Gene target
-
Gene symbolDTX1
-
Short nameAnti-Deltex 1
-
TechniqueAntibody, antibodies against human proteins, antibodies for
-
HostRabbit (Oryctolagus cuniculus)
-
IsotypeImmunoglobulin G (IgG)
-
Alternative nameDeltex 1 Polyclonal Antibody
-
Alternative techniqueantibodies
-
Gene info
-
Identity
-
Gene
-
Long gene namedeltex E3 ubiquitin ligase 1
-
Synonyms gene name
- deltex homolog 1 (Drosophila)
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year1998-05-15
-
Entrez gene record
-
Pubmed identfication
-
Classification
- Ring finger proteins
-
VEGA ID
MeSH Data
-
Name
-
ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data