Cytokeratin 14 (KRT14) (Squamous Cell Marker) Mouse Monoclonal Antibody

• Catalog number
  MBS438196
• Price
  Please ask
• Size
  0.1 mg (With BSA & Azide at 0.2mg/mL)

• Products_type
  Antibody
• Products_short_name
  [Cytokeratin 14 (KRT14)]
• Products_name_syn
  [CK-14; Dowling Meara; ebs3; ebs4; Epidermolysis Bullosa Simplex; k14; Keratin 14; Keratin Type I Cytoskeletal 14; Koebner; krt14; NFJ]
• Other_names
  [keratin, type I cytoskeletal 14; Keratin, type I cytoskeletal 14; keratin, type I cytoskeletal 14; keratin 14; Cytokeratin-14; CK-14; Keratin-14; K14]
• Products_gene_name
  [KRT14]
• Other_gene_names
  [KRT14; KRT14; K14; NFJ; CK14; EBS3; EBS4; CK-14; K14]
• Clonality
  Monoclonal
• Clone
  [SPM263]
• Reactivity
  Human, Mouse, Rat
• Specificity
  Cytokeratin 14 (CK14) belongs to the type I (or A or acidic) subfamily of low molecular weight keratins and exists in combination with keratin 5 (type II or B or basic). CK14 is found in basal cells of squamous epithelia, some glandular epithelia, myoepithelium, and mesothelial cells. Anti-CK14 is useful in differentiating squamous cell carcinomas from poorly differentiated epithelial tumors. Anti-CK14 is one of the specific basal markers for distinguishing between basal and non-basal subtypes of breast carcinomas. Anti-CK14 is also a good marker for differentiation of intraductal from invasive salivary duct carcinoma by the positive staining of basal cells surrounding the in-situ neoplasm as well as for differentiation of benign prostate from prostate carcinoma. Furthermore, this antibody has been useful in separating oncocytic tumors of the kidney from its renal mimics, and in identifying metaplastic carcinomas of the breast.
• Form
  200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
• Storage_stability
  Antibody with azide - store at 2 to 8 degree C. Antibody without azide - store at -20 to -80 degree C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
• Tested_application
  Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC) Formalin
• Properties
  If you buy Antibodies supplied by MyBioSource they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Description
  For cells, cell lines and tissues in culture till half confluency.
• About
  Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
• Test
  Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
• Latin name
  Mus musculus
• French translation
  anticorps

• Gene target
  Cytokeratin   KRT14   Squamous   Monoclonal  
• Gene symbol
  KRT14
• Short name
  Cytokeratin 14 (KRT14) (Squamous ) Mouse Monoclonal Antibody
• Technique
  Mouse monoclonal, Antibody, Mouse, antibodies against human proteins, antibodies for, Component cell markers and DNA bp. markers are genetic markers er genes or DNA sequences with a known location on a chromosome that can be used to identify individuals or species. Protein markers in kDA. Monoclonals or monoclonal antibodies, mouses, mouse monoclonals
• Host
  Mouse, Murine monoclonal antibodies or Mabs are often conjugated and the isotype is IgG.
• Isotype
  IgG3
• Species
  Mouse, Mouses
• Alternative name
  Cytokeratin 14 (KRT14) (Squamous cellular detection labelled) Mouse monoclonal (antibody to-)
• Alternative technique
  antibodies, murine
• Tissue
  cell

Gene info

• Identity
  HGNC:6416
• Gene
  KRT14
• Long gene name
  keratin 14
• Synonyms gene
  • EBS3
  • EBS4
• Synonyms gene name
  • keratin 14 (epidermolysis bullosa simplex, Dowling-Meara, Koebner)
  • keratin 14, type I
• Synonyms name
  • epidermolysis bullosa simplex, Dowling-Meara, Koebner
• GenBank acession
  • BC002690
• Locus
  17q21.2
• Discovery year
  1992-04-09
• Entrez gene record
  3861
• Pubmed identfication
  • 1717157
  • 16831889
• RefSeq identity
  • NM_000526
• Classification
  • Keratins, type I
• VEGA ID
  OTTHUMG00000133426

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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