CYP46 Antibody

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• Catalog number
  bs-5051R
• Price:

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• Size
  0.1ml

# #

• Long name
  CYP46 Primary Polyclonal Antibody
• Also known as
  CYP46 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  CYP46
• Specificity
  This is a highly specific antibody against CYP46.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CYP46
• Gene ID number
  10858
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  The Cyp46 gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is expressed exclusively in the brain, where it converts cholesterol to 24S-hydroxycholesterol by adding a hydroxyl group to cholesterol, producing a product that is more soluble than cholesterol and able to be exported from the brain.Cyp46 is also known as 24S-cholesterol hydroxylase.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  Cholesterol 24-hydroxylase; CP46; CYP46; cytochrome P450 family 46; CP46A_HUMAN.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

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• Gene target
  CYP46  
• Gene symbol
  CYP46A1
• Short name
  Anti-CYP46
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  CYP46 Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:2641
• Gene
  CYP46A1
• Long gene name
  cytochrome P450 family 46 subfamily A member 1
• Synonyms gene
  • CYP46
• Synonyms gene name
  • cytochrome P450, subfamily 46 (cholesterol 24-hydroxylase)
  • cytochrome P450, family 46, subfamily A, polypeptide 1
• GenBank acession
  • AF094480
• Locus
  14q32.2
• Discovery year
  1999-08-20
• Entrez gene record
  10858
• Pubmed identfication
  • 10377398
• Classification
  • Cytochrome P450 family 46
• VEGA ID
  OTTHUMG00000171510

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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