Cyclin D1 (Thr286) Antibody
-
Catalog number
bs-3124R
-
Price
Please ask
-
Size
0.1ml
-
-
Long name
Cyclin D1 (Thr286) Primary Polyclonal Antibody
-
Also known as
Cyclin D1 (Thr286) PAb
-
Category
Primary Antibodies
-
Conjugation
Unconjugated
-
Target Antigen
Cyclin D1 Thr286
-
Specificity
This is a highly specific antibody against Cyclin D1 Thr286.
-
Modification s
Phosphorylation
-
Modification site s
Thr286
-
Clonality
Polyclonal antibody
-
Clone number
Polyclonal antibody
-
Concentration
1ug per 1ul
-
Source
KLH conjugated synthetic phosphopeptide derived from human Cyclin D1 around the phosphorylation site of Thr286
-
Gene ID number
595
-
Tested Applications
WB, IHC-P, IF(IHC-P)
-
Recommended dilutions
WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
-
Cross reactivity
Human
-
Cross reactive species details
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
-
Background of the target antigen
The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance throughout the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with tumor suppressor protein Rb and the expression of this gene is regulated positively by Rb. Mutations, amplification and overexpression of this gene, which alters cell cycle progression, are observed frequently in a variety of tumors and may contribute to tumorigenesis. [provided by RefSeq, Jul 2008].
-
Purification method
This antibody was purified via Protein A.
-
Storage conditions
Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
-
Synonym names
Cyclin D1 phospho T286; p-Cyclin D1 phospho T286; AI327039; B cell ccl/lymphoma 1; B cell leukemia 1; B-cell CLL/lymphoma 1; B-cell leukemia 1; B-cell lymphoma 1 protein; BCL-1; BCL1; BCL1 oncogene; CCND 1; CCND1; CCND1 protein; CCND1/FSTL3 fusion gene, included; CCND1/IGHG1 fusion gene; CCND1/IGHG1 fusion gene, included; CCND1/IGLC1 fusion gene, included; CCND1/PTH fusion gene, included; cD1; Cyclin D1; Cyl-1; D11S287E; G1/S specic cyclin D1; MGC137744; Parathyroid adenomatosis 1; PRAD1; PRAD1 oncogene; U21B31; CCND1_HUMAN.
-
Properties
If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
French translation
anticorps
-
Gene target
-
Short name
Anti-Cyclin D1 Thr286
-
Technique
Antibody, antibodies against human proteins, antibodies for
-
Host
Rabbit (Oryctolagus cuniculus)
-
Isotype
Immunoglobulin G (IgG)
-
Alternative name
Cyclin D1 (Thr286) Polyclonal Antibody
-
Alternative technique
antibodies
-
MeSH Data
-
Name
-
Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Similar products