Curcumin, Curcuma longa (High Purity)
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Catalog number
1850-50
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Price
Please ask
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Size
50 mg
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Alternative_name
1,7-bis(4-Hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione, Diferuloylmethane
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Description
Cell-permeable. An antioxidant and dual inhibitor of 5-lipoxygenase (IC₅₀ = 8 µM) and cyclooxygenase (COX) (IC₅₀ = 52 µM). Also inhibits glutathione S-transferase, induction of nitric oxide (NO) in activated macrophages and inhibits EGF-induced tyrosine phosphorylation of EGF receptors. Also shown to be a p300/CREB-binding protein-specific inhibitor of histone acetyltransferase, inhibiting the acetylation of histones H3 and H4 with an IC₅₀ of ~25 µM. Does not affect p300/CREB binding protein-associated factor (PCAF).
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CAS Number
458-37-7
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Structure Available
Yes
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Salt Form
No
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Molecular Formula
C₂₁H₂₀O₆
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Molecular Weight
368.38
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Cell Permeable
Yes
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Purity
≥98%
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Solubilities
DMSO (25 mg/ml) or EtOH (10 mg/ml)
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Handling
Protect from air and light
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Tag Line
A potent antioxidant
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Storage Condition
-20°C
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Shipping Condition
gel pack
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Shelf Life
24 months
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MDL Number
MFCD00008365
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PubChem CID
969516
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SMILES
COC1=C(C=CC(=C1)C=CC(=O)CC(=O)C=CC2=CC(=C(C=C2)O)OC)O
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InChi
InChI=1S/C21H20O6/c1-26-20-11-14(5-9-18(20)24)3-7-16(22)13-17(23)8-4-15-6-10-19(25)21(12-15)27-2/h3-12,24-25H,13H2,1-2H3/b7-3+,8-4+
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InChi Key
VFLDPWHFBUODDF-FCXRPNKRSA-N
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MSDS Available
Yes
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Gene target
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Short name
Curcumin, Curcuma longa ( Purity)
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Alternative name
Curcumin, Curcuma longa (High Purity)
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Product images
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