CRK (Ser41) Antibody

• Catalog number
  bs-5264R
• Price
  Please ask
• Size
  0.1ml

• Long name
  CRK (Ser41) Primary Polyclonal Antibody
• Also known as
  CRK (Ser41) PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  CRK Ser41
• Specificity
  This is a highly specific antibody against CRK Ser41.
• Modification s
  Phosphorylation
• Modification site s
  Ser41
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  KLH conjugated synthetic phosphopeptide derived from human CRK around the phosphorylation site of Ser41 [DS(p-S)TS]
• Gene ID number
  1398
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  This gene encodes a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. The product of this gene has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Two alternative transcripts encoding different isoforms with distinct biological activity have been described.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  p-CRKSer41; p-CRKS41; CRK CRK isoform 2; CRK isoform II; CRKII; p38; Proto oncogene C crk; v crk avian sarcoma virus CT10 oncogene homolog ; v crk sarcoma virus CT10 oncogene homolog; v crk sarcoma virus CT10 oncogene homolog avian; Adapter molecule crk; Avian sarcoma virus CT10 v crk oncogene homolog; CRK_HUMAN.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  CRK   Ser41  
• Gene symbol
  CRK
• Short name
  Anti-CRK Ser41
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  CRK (Ser41) Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:2362
• Gene
  CRK
• Long gene name
  CRK proto-oncogene, adaptor protein
• Synonyms gene name
  • v-crk avian sarcoma virus CT10 oncogene homolog
• GenBank acession
  • D10656
• Locus
  17p13.3
• Discovery year
  1992-12-07
• Entrez gene record
  1398
• Pubmed identfication
  • 1690891
• RefSeq identity
  • NM_016823
• Classification
  • SH2 domain containing
• VEGA ID
  OTTHUMG00000090317

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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