Chordin Antibody

• Catalog number
  bs-11831R
• Price
  Please ask
• Size
  0.1ml

• Long name
  Chordin Primary Polyclonal Antibody
• Also known as
  Chordin PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  Chordin
• Specificity
  This is a highly specific antibody against Chordin.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Chordin
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  The patterning of the CNS relies on the interaction of multiple signaling molecules such as Sonic Hedgehog, Wnts, and BMPs and their antagonists Chordin and Noggin. At midgastrula, expression of Noggin overlaps that of Chordin. Chordin is a key developmental protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta-like bone morphogenetic proteins and sequestering them in latent complexes. The gene which encodeschordin maps to human chromosome 3q27. Noggin is a secreted protein that binds and inactivates members of the transforming growth factor-beta (TGF-beta) superfamily of signaling proteins, such as BMP-2,4,7. The gene which encodes noggin maps to human chromosome 17q22.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  Chordin; Chrd; CHRD_HUMAN; MGC133038; Shortgastrulation protein; SOG.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Chordin  
• Gene symbol
  CHRD, CHRDL2, KCP
• Short name
  Anti-Chordin
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  Chordin Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:1949
• Gene
  CHRD
• Long gene name
  chordin
• GenBank acession
  • AF076612
• Locus
  3q27.1
• Discovery year
  1998-11-06
• Entrez gene record
  8646
• Pubmed identfication
  • 9782094
  • 11472837
• RefSeq identity
  • NM_003741
• Classification
  • Chordin family
• VEGA ID
  OTTHUMG00000141267

Gene info

• Identity
  HGNC:24168
• Gene
  CHRDL2
• Long gene name
  chordin like 2
• Synonyms
  • BNF1
• GenBank acession
  • AL110168
• Locus
  11q13.4
• Discovery year
  2004-01-28
• Entrez gene record
  25884
• Pubmed identfication
  • 12853144
  • 12975309
• Classification
  • Chordin family
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000165623

Gene info

• Identity
  HGNC:17585
• Gene
  KCP
• Long gene name
  kielin cysteine rich BMP regulator
• Synonyms gene
  • CRIM2
• Synonyms gene name
  • cysteine rich BMP regulator 2 (chordin-like)
  • kielin/chordin-like protein
• Synonyms
  • FLJ33365
  • NET67
• Synonyms name
  • kielin
• GenBank acession
  • AK122706
• Locus
  7q32.1
• Discovery year
  2005-07-25
• Entrez gene record
  375616
• Pubmed identfication
  • 15793581
• RefSeq identity
  • NM_199349
• Classification
  • Cysteine rich transmembrane BMP regulators
• VEGA ID
  OTTHUMG00000158363

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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