CHIR 98014 for cell activation

CHIR 98014 for cell activation is available 2 times from Biovision labs

2595-1 | CHIR-98014 for cell activationsize: 1 mg | 164.55 USD

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2595-5 | CHIR-98014 for cell activationsize: 5 mg | 479.74 USD

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  • Description
    Cell-permeable. CHIR-98014 is a potent, selective and ATP-competitive inhibitor of GSK3α and GSK3β (IC₅₀ = 0.65 and 0.58 nM, respectively). In addition, CHIR-98014 displays 500 to greater than 1000-fold selectivity towards GSK3 than other protein kinases such as cdc2 and ERK2. CHIR98014 also reduces tau phosphorylation in rat brains and supports Wnt signaling during osteogenesis.
  • Peptide sequence
    N/A
  • CAS number
    556813-39-9
  • Molecular weight
    486.31
  • Category
    Biochemicals
  • Other name
    6-N-[2-[[4-(2,4-dichlorophenyl)-5-imidazol-1-ylpyrimidin-2-yl]amino]ethyl]-3-nitropyridine-2,6-diamine; CT 98014
  • Molecular formula
    C₂₀H₁₇Cl₂N₉O₂
  • Physical appearance
    Crystalline solid
  • Supplied with
    N/A
  • Is this a salt?
    No
  • Is it cell-permeable?
    Yes
  • Purification
    >98% by HPLC
  • Reconstitute instructions
    DMSO (~ 4 mg/ml)
  • Storage condition
    -20 ̊C
  • Shipping condition
    Gel pack
  • Maximum time for storage
    36 months
  • Storage instructions
    Protect from air and light
  • Additional description
    For cells, cell lines and tissues in culture till half confluency.
  • Gene target
  • Short name
    CHIR-98014 for activation
  • Technique
    activation
  • Alternative name
    CHIR-98014 to measure cellular activation
  • Tissue
    cell
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