CDK6 Antibody ( DCS90)

• Catalog number
  MA1021
• Price
  Please ask
• Size
  0,1 mg

• Target antigen
  CDK6
• Clonality
  Monoclonal antibody
• Clone
  DCS-90
• Raised in
  mice
• Type of the antibody
  IgG1 monoclonal antibody
• Product form
  freeze-dried
• Reacts with species
  Human, mouse, rat
• Analyses
  WB,ICC
• Immunogen
  Recombinant human Cdk6 protein.
• Product configuration
  Mouse ascites fluid, 1.2% Na acetate, 2mg BSA, with 0.01mg NaN3 as preservative.
• Purification
  Ascites
• Solubilization
  The powdered antibody should be dissolved in 1ml of PBS buffer to achieve final concentration of 100ug/ml.
• Storage condtions
  Keep the CDK6 Antibody ( DCS90)at minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.
• Tips
  The CDK6 Antibody ( DCS90) did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.
• Background
  The cyclin-dependent protein kinases(CDKs) regulate major cell cycle transitions in eukaryotic cells. Cyclin-dependent kinase-6(CDK6) is the earliest inducible member of the CDK family in human T lymphocytes, involved in growth factor stimulation and cell cycle progression. Germline mutations in CDK6 do not make a significant contribution to melanoma predisposition. CDK6 gene is mapped at 7q21-q22.
• Related articles
  1. Chilosi, M.; Doglioni, C.; Yan, Z.; Lestani, M.; Menestrina, F.; Sorio, C.; Benedetti, A.; Vinante, F.; Pizzolo, G.; Inghirami, G. : Differential expression of cyclin-dependent kinase 6 in cortical thymocytes and T-cell lymphoblastic lymphoma/leukemia. Am. J. Path. 152: 209-217, 1998. 2. Shennan, M. G.; Badin, A.-C.; Walsh, S.; Summers, A.; From, L.; McKenzie, M.; Goldstein, A. M.; Tucker, M. A.; Hogg, D.; Lassam, N. : Lack of germline CDK6 mutations in familial melanoma. Oncogene 19: 1849-1852, 2000. 3. Lien, H.-C.; Lin, C.-W.; Huang, P.-H.; Chang, M.-L.; Hsu, S.-M. : Expression of cyclin-dependent kinase 6 (cdk6) and frequent loss of CD44 in nasal-nasopharyngeal NK/T-cell lymphomas: comparison with CD56-negative peripheral T-cell lymphomas. Lab. Invest. 80: 893-900, 2000.
• Gene Name
  CDK6
• Protein Name
  Cyclin-dependent kinase 6
• Gene Full Name
  cyclin-dependent kinase 6
• Synonyms
  CDKN6|PLSTIRE|Cell division protein kinase 6|Serine/threonine-protein kinase PLSTIRE
• Uniprot ID
  Human(Q00534), Mouse(Q64261), Rat(F1MA87)
• Entrez GeneID
  Human(1021), Mouse(12571), Rat(114483)
• Properties
  If you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  CDK6   DCS90  
• Gene symbol
  CDK6, CDK6-AS1
• Short name
  CDK6 Antibody ( DCS90)
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Alternative name
  CDK6 (antibody to-) ( DCS90)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:1777
• Gene
  CDK6
• Long gene name
  cyclin dependent kinase 6
• Synonyms
  • PLSTIRE
• Locus
  7q21.2
• Discovery year
  1994-02-14
• Entrez gene record
  1021
• Pubmed identfication
  • 1639063
• Classification
  • Cyclin dependent kinases
• VEGA ID
  OTTHUMG00000131697
• Locus Specific Databases
  • LRG_991

Gene info

• Identity
  HGNC:40141
• Gene
  CDK6-AS1
• Long gene name
  CDK6 antisense RNA 1
• Synonyms
  • BALR-2
• Synonyms name
  • B-ALL associated long RNA-2
• Locus
  7q21.2
• Discovery year
  2019-07-24
• Entrez gene record
  101927497
• Pubmed identfication
  • 25681502
• RefSeq identity
  • NR_110086
• Classification
  • Antisense RNAs

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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