CDC27 (Thr244) Antibody

• Catalog number
  bs-5268R
• Price
  Please ask
• Size
  0.1ml

• Long name
  CDC27 (Thr244) Primary Polyclonal Antibody
• Also known as
  CDC27 (Thr244) PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  CDC27 Thr244
• Specificity
  This is a highly specific antibody against CDC27 Thr244.
• Modification s
  Phosphorylation
• Modification site s
  Thr244
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  KLH conjugated synthetic phosphopeptide derived from human CDC27 around the phosphorylation site of Thr244
• Gene ID number
  996
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae protein Cdc27, and the gene product of Schizosaccharomyces pombe nuc 2. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eucaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction. This protein was shown to interact with mitotic checkpoint proteins including Mad2, p55CDC and BUBR1, and thus may be involved in controlling the timing of mitosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  ANAPC3; Anaphase Promoting Complex 3; Anaphase promoting complex protein 3; Anaphase Promoting Complex Subunit 3; Anaphase-promoting complex subunit 3; APC 3; APC3; APC-3; Cdc 27; Cdc27; Cdc-27; CDC27 homolog; CDC27_HUMAN; CDC27Hs; Cell division cycle 27; Cell division cycle protein 27 homolog; H NUC; H-NUC; HNUC; NUC2 homolog.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  CDC27   Thr244  
• Gene symbol
  CDC27
• Short name
  Anti-CDC27 Thr244
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  CDC27 (Thr244) Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:1728
• Gene
  CDC27
• Long gene name
  cell division cycle 27
• Synonyms gene
  • D0S1430E
  • D17S978E
• Synonyms gene name
  • D0S1430E, D17S978E
• Synonyms
  • APC3
  • ANAPC3
  • NUC2
• Synonyms name
  • anaphase promoting complex subunit 3
• GenBank acession
  • U00001
• Locus
  17q21.32
• Discovery year
  1994-02-23
• Entrez gene record
  996
• Pubmed identfication
  • 8234252
• Classification
  • Anaphase promoting complex
  • Tetratricopeptide repeat domain containing
• VEGA ID
  OTTHUMG00000166429

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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