CD68, human recombinant
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Catalog number7343-50
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PricePlease ask
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Size50 ug
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SynonymsMacrosialin, GP110, LAMP4, SCARD1
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Alternative_namesMacrosialin, GP110, LAMP4, SCARD1
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DescriptionA glycoprotein which binds to low density lipoprotein
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RecombinantYes
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SourceE. coli
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Purity by SDS PAGE≥85%
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AssaySDS-PAGE
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Molecular Weight34.1 kDa (323 aa, 22-319 aa + His Tag), confirmed by MALDI-TOF.
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Storage Temp-80°C
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ShippingDry Ice
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Shelf Life12 months
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Concentration1 mg/ml
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AppearanceLiquid
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Physical form description1 mg/ml in 20 mM Tris-HCl buffer (pH 8.0) containing 0.1 M NaCl, 1 M Urea and 10% glycerol.
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Background InformationMacrosialin, also known as CD68, is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. It is found in cytoplasmic granules and in the cytoplasm of various non-hematopoietic tissues including liver and kidney tubules and glomeruli. CD68 is also found, to a lesser extent, on the surface of macrophages, monocytes, neutrophils, basophils and large lymphocytes. Recombinant human CD68 protein, fused to His-tag at N-terminus, was expressed in E.coli.
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Amino acid sequenceMGSSHPLHHH SSGLVPRGSH MGSHMNDCPH KKSATLLPSF TVTPTVTEST GTTSHRTTKS HKTTTHRTTT TGTTSHGPTT ATHNPTTTSH GNVTVHPTSN STATSQGPST ATHSPATTSH GNATVHPTSN STATSPGFTS SAHPEPPPPS PSPSPTSKET IGDYTWTNGS QPCVHLQAQI QIRVMYTTQG GGEAWGISVL NPNKTKVQGS CEGAHPHLLL SFPYGHLSFG FMQDLQQKVV YLSYMAVEYN VSFPHAAQWT FSAQNASLRD LQAPLGQSFS CSNSSIILSP AVHLDLLSLR LQAAQLPHTG VFGQSFSCPS DRS
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HandlingCentrifuge the vial prior to opening.
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UsageFor Research Use Only! Not to be used in humans
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PropertiesHuman proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Additional sourceRecombinants or rec. proteins
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Grouprecombinants
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Gene target
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Gene symbolCD68
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Short nameCD68, recombinant
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TechniqueRecombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
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SpeciesHuman, Humans
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Alternative nameCD68 molecule, H. sapiens Rec.
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Alternative techniquerec
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Alternative to gene targetCD68 molecule, GP110 and LAMP4 and SCARD1, CD68 and IDBG-25923 and ENSG00000129226 and 968, Plasma membranes, Cd68 and IDBG-191443 and ENSMUSG00000018774 and 12514, CD68 and IDBG-635034 and ENSBTAG00000000133 and 504960
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Gene info
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Identity
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Gene
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Long gene nameCD68 molecule
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Synonyms gene name
- CD68 antigen
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1993-06-11
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Scavenger receptors
- Lysosome associated membrane proteins
- CD molecules
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VEGA ID
MeSH Data
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Name
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ConceptScope note: The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data