IL3RA Antibody

• Catalog number
  R30698
• Price
  Please ask
• Size
  0.1mg

• Category
  Antibody
• Concentration
  0.5mg/ml if reconstituted with 0.2ml sterile DI water
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  IL3RA
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB
• Recommended dilutions
  Western blot: 0.5-1ug/ml
• Notes
  The stated application concentrations are suggested starting amounts. Titration of the IL3RA antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This IL3RA antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  P26951
• Purity
  Antigen affinity
• Description
  IL3RA (Interleukin 3 receptor alpha), also called CD123 (Cluster of Differentiation 123), is a human gene. The protein encoded by this gene is an interleukin 3 specific subunit of a heterodimeric cytokine receptor which is composed of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3(IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5(IL5). The genomic structures of IL3RA and CSF2RA are very similar and share an additional exon encoding part of the C-terminal domain not found in other members of this gene family. As in human hematopoietic cells, IL3 and GMCSF competed for binding in fibroblasts expressing the cDNAs for IL3RA, CSF2RA, and the common beta subunit, indicating that different alpha subunits compete for a common beta subunit.
• Immunogen
  An amino acid sequence from the middle region of human IL3RA (QYDLYLNVANRRQQYEC) was used as the immunogen for this IL3RA antibody.
• Storage
  After reconstitution, the IL3RA antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  IL3RA  
• Gene symbol
  IL3RA
• Short name
  Anti-IL3RA
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibodies to IL3RA
• Alternative technique
  antibodies
• Alternative to gene target
  interleukin 3 receptor, alpha (low affinity), CD123 and hIL-3Ra and IL3R and IL3RAY and IL3RX and IL3RY, IL3RA and IDBG-39718 and ENSG00000185291 and 3563, protein binding, Plasma membranes, Il3ra and IDBG-132811 and ENSMUSG00000068758 and 16188

Gene info

• Identity
  HGNC:6012
• Gene
  IL3RA
• Long gene name
  interleukin 3 receptor subunit alpha
• Synonyms gene name
  • interleukin 3 receptor, alpha (low affinity)
• Synonyms
  • CD123
• GenBank acession
  • M74782
• Locus
  Xp22.3 and Yp13.3
• Discovery year
  1992-10-28
• Entrez gene record
  3563
• Pubmed identfication
  • 1833064
• Classification
  • Pseudoautosomal region 1
  • CD molecules
  • Interleukin receptors
• VEGA ID
  OTTHUMG00000021059

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Similar products