CCR5 Antibody

• Catalog number
  F47455-0.4ML
• Price
  Please ask
• Size
  0.4 ml

• Category
  Antibody
• Concentration
  In 1X PBS, pH 7.4, with 0.09% sodium azide
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  CCR5
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, ELISA
• Recommended dilutions
  Western blot: 1:1000
• Notes
  Titration of the CCR5 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This CCR5 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  P51681
• Purity
  Antigen affinity
• Description
  This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this gene was also detected in a promyeloblastic cell line, suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation. This gene is located at the chemokine receptor gene cluster region. Two transcript variants encoding the same protein have been found for this gene.
• Immunogen
  A portion of amino acids 151-177 from the human protein was used as the immunogen for this CCR5 antibody.
• Storage
  Aliquot the CCR5 antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  CCR5  
• Gene symbol
  CCR5
• Short name
  Anti-CCR5
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit Ig
• Alternative name
  Antibodies to CCR5
• Alternative technique
  antibodies
• Alternative to gene target
  chemokine (C-C motif) receptor 5 (gene/pseudogene), CC-CKR-5 and CCCKR5 and CCR-5 and CD195 and CKR-5 and CKR5 and CMKBR5 and IDDM22, CCR5 and IDBG-30229 and ENSG00000160791 and 1234, chemokine (C-C motif) ligand 5 binding, Cell surfaces, CCR5 and IDBG-646247 and ENSBTAG00000008099 and 497017

Gene info

• Identity
  HGNC:1606
• Gene
  CCR5
• Long gene name
  C-C motif chemokine receptor 5
• Synonyms gene
  • CMKBR5
• Synonyms gene name
  • chemokine (C-C motif) receptor 5
  • chemokine (C-C motif) receptor 5 (gene/pseudogene)
  • C-C motif chemokine receptor 5 (gene/pseudogene)
• Synonyms
  • CKR-5
  • CC-CKR-5
  • CKR5
  • CD195
  • IDDM22
• Locus
  3p21.31
• Discovery year
  1996-05-15
• Entrez gene record
  1234
• Pubmed identfication
  • 8639485
  • 9284370
  • 20210993
• RefSeq identity
  • NM_000579
• Classification
  • C-C motif chemokine receptors
  • CD molecules
• VEGA ID
  OTTHUMG00000133481

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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