CBL2 (Tyr674) Antibody

• Catalog number
  bs-4071R
• Price
  Please ask
• Size
  0.1ml

• Long name
  CBL2 (Tyr674) Primary Polyclonal Antibody
• Also known as
  CBL2 (Tyr674) PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  CBL2 Tyr674
• Specificity
  This is a highly specific antibody against CBL2 Tyr674.
• Modification s
  Phosphorylation
• Modification site s
  Tyr674
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  KLH conjugated synthetic phosphopeptide derived from human C CBL around the phosphorylation site of Tyr674
• Gene ID number
  867
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Participates in signal transduction in hematopoietic cells. Adapter protein that functions as a negative regulator of many signaling pathways that start from receptors at the cell surface. Acts as an E3 ubiquitin-protein ligase, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and then transfers it to substrates promoting their degradation by the proteasome. Recognizes activated receptor tyrosine kinases, including PDGFA, EGF and CSF1, and terminates signaling.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  C CBL Tyr674; CBL2 Tyr674; CBL2 Y674; p-CBL2 Tyr674; p-CBL2 Y674; C CBL; Cas Br M murine ecotropic retroviral transforming sequence; Cas-Br-M murine ecotropic retroviral transforming sequence; Casitas B lineage lymphoma proto oncogene; Casitas B-lineage lymphoma proto-oncogene; CBL 2; cbl; CBL_HUMAN; CBL2; E3 ubiquitin protein ligase CBL; E3 ubiquitin-protein ligase CBL; Oncogene CBL2; Proto oncogene c CBL; Proto-oncogene c-CBL; RGD1561386; RING finger protein 55; RNF55; Signal transduction protein CBL.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  CBL2   Tyr674  
• Gene symbol
  CBL
• Short name
  Anti-CBL2 Tyr674
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  CBL2 (Tyr674) Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:1541
• Gene
  CBL
• Long gene name
  Cbl proto-oncogene
• Synonyms gene
  • CBL2
• Synonyms gene name
  • Cas-Br-M (murine) ecotropic retroviral transforming sequence
  • Cbl proto-oncogene, E3 ubiquitin protein ligase
• Synonyms
  • RNF55
  • c-Cbl
• Synonyms name
  • oncogene CBL2
• GenBank acession
  • X57110
• Locus
  11q23.3
• Discovery year
  1989-06-30
• Entrez gene record
  867
• Pubmed identfication
  • 2013228
• RefSeq identity
  • NM_005188
• Classification
  • Ring finger proteins
• VEGA ID
  OTTHUMG00000166170
• Locus Specific Databases
  • LRG_608

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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