Caspase-9, active, cleaved (CASP-9, Apoptotic Protease Mch-6, Apoptotic Protease-activating Factor 3, APAF-3, ICE-like Apoptotic Protease 6, ICE-LAP6, CASP9, MCH6) Antibody
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Catalog numberMBS644637
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PricePlease ask
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Size0.05 ml
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Alternative name1Anti-Caspase-9, active, cleaved (CASP-9, Apoptotic Protease Mch-6, Apoptotic Protease-activating Factor 3, APAF-3, ICE-like Apoptotic Protease 6, ICE-LAP6, CASP9, MCH6)
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Alternative name2Caspase-9, active, cleaved (CASP-9, Apoptotic Protease Mch-6, Apoptotic Protease-activating Factor 3, APAF-3, ICE-like Apoptotic Protease 6, ICE-LAP6, CASP9, MCH6)
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Alternative name3Caspase-9, active, cleaved (CASP-9, Apoptotic Protease Mch-6, Apoptotic Protease-activating Factor 3, APAF-3, ICE-like Apoptotic Protease 6, ICE-LAP6, CASP9, MCH6)
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Alternative name4Caspase-9, active, cleaved
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Alternative name5Anti -Caspase-9, active, cleaved (CASP-9, Apoptotic Protease Mch-6, Apoptotic Protease-activating Factor 3, APAF-3, ICE-like Apoptotic Protease 6, ICE-LAP6, CASP9, MCH6)
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Other namesChain F, Structure Of Cleaved, Card Domain Deleted Caspase-9; N/A
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Gene nameN/A
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Gene name synonimsN/A
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Other gene namesN/A
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CategoryAntibodies
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ClonalityPolyclonal
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Immunoglobulin isotypeIgG
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ClonePolyclonal antibody
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Host organismHost: Rabbit; Source: Human
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Species reactivityCanine, Human, Mouse, Rat
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Specificity and cross reactivityRecognizes human active, cleaved Caspase-9. May recognize the proform of caspase-9. On Western Blot, the proform is detected at ~50-60kD, the large subunit at ~35kD, and the small subunit at ~15kD. Intermediate cleavage forms may also be observed at ~21kD. Species Crossreactivity: canine, gerbil, mouse and rat.
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Purification methodSerum
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Form AppearanceSupplied as a liquid, 0.05% sodium azide.
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ConcentrationN/A
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Storage and shippingStore at 4 degrees Celsius for short term storage.. Aliquot to avoid repeated freezing and thawing. For optimal long term storage, productone should be kept at -20 degrees Celsius. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
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Tested forWestern Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC)
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Descriptionproductone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against. Properly used, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in. Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, they are inexpensive to manufacture and respectively to buy, the time needed for production is considerably shorter. Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions. To obtain more detailed information on productone, please, refer to the full product datasheet.
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AdvisoryIn order to retain the quality and the affinity of productone unchanged, please, avoid cycles of freezing and thawing. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
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PropertiesIf you buy Antibodies supplied by MBS Polyclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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Additional descriptionHuman and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways. Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells.
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French translationanticorps
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Gene target
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Gene symbolCASP9, CASP1, CASP5, CES2, CARD18, CARD16, CASP4, CASP7, MIR9-3, KRTAP5-3
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Short nameCaspase-9, active, cleaved (CASP-9, Apoptotic Protease Mch-6, Apoptotic Protease-activating Factor 3, APAF-3, ICE-like Apoptotic Protease 6, ICE-LAP6, CASP9, MCH6) Antibody
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TechniqueAntibody, antibodies against human proteins, antibodies for
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Alternative namecaspase-9, functionnal, cleaved (caspase-9, Apoptotic Protease Mch-6, Apoptotic Protease-activating Factor 3, Apoptotic protease activating factor-3, ICE-like Apoptotic Protease 6, ICE-LAP6, caspase 9, apoptosis-related cysteine peptidase, MCH6) (antibody to-)
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Alternative techniqueantibodies
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Alternative to gene targetcaspase 9, apoptosis-related cysteine peptidase, APAF-3 and APAF3 and ICE-LAP6 and MCH6 and PPP1R56, CASP9 and IDBG-90895 and ENSG00000132906 and 842, protein kinase binding, nuclei, Casp9 and IDBG-202405 and ENSMUSG00000028914 and 12371, CASP9 and IDBG-635833 and ENSBTAG00000002472 and 100140945
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Gene info
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Identity
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Gene
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Long gene namecaspase 9
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Synonyms gene name
- caspase 9, apoptosis-related cysteine protease
- caspase 9, apoptosis-related cysteine peptidase
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1996-11-11
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Caspases
- Apoptosome
- Caspase recruitment domain containing
- Protein phosphatase 1 regulatory subunits
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namecaspase 1
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Synonyms gene
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Synonyms gene name
- caspase 1, apoptosis-related cysteine protease (interleukin 1, beta, convertase)
- caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)
- caspase 1, apoptosis-related cysteine peptidase
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1992-05-07
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Caspases
- Caspase recruitment domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namecaspase 5
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Synonyms gene name
- caspase 5, apoptosis-related cysteine protease
- caspase 5, apoptosis-related cysteine peptidase
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Synonyms
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Locus
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Discovery year1996-09-13
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Caspases
- Caspase recruitment domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namecarboxylesterase 2
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Synonyms gene name
- carboxylesterase 2 (intestine, liver)
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Synonyms
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GenBank acession
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Locus
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Discovery year1993-09-30
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Carboxylesterases
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namecaspase recruitment domain family member 18
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Synonyms gene name
- caspase recruitment domain family, member 18
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Synonyms
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GenBank acession
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Locus
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Discovery year2008-09-02
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Caspase recruitment domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namecaspase recruitment domain family member 16
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Synonyms gene name
- caspase recruitment domain family, member 16
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Synonyms
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Locus
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Discovery year2008-09-15
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Entrez gene record
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Pubmed identfication
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Classification
- Caspase recruitment domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namecaspase 4
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Synonyms gene name
- caspase 4, apoptosis-related cysteine protease
- caspase 4, apoptosis-related cysteine peptidase
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Synonyms
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GenBank acession
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Locus
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Discovery year1996-07-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Caspases
- Caspase recruitment domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namecaspase 7
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Synonyms gene name
- caspase 7, apoptosis-related cysteine protease
- caspase 7, apoptosis-related cysteine peptidase
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Synonyms
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GenBank acession
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Locus
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Discovery year1996-07-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Caspases
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namemicroRNA 9-3
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Synonyms gene
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Synonyms
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Locus
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Discovery year2004-04-23
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Entrez gene record
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RefSeq identity
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Classification
- MicroRNA MIR9 family
Gene info
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Identity
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Gene
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Long gene namekeratin associated protein 5-3
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Synonyms
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GenBank acession
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Locus
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Discovery year2003-12-01
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Entrez gene record
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Pubmed identfication
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Classification
- Keratin associated proteins
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Theoretical representations that simulate the behavior or activity of chemical processes or phenomena; includes the use of mathematical equations, computers, and other electronic equipment.
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Tree numbers
- E05.599.495