Caspase-8L (CASP8, Caspase-8, CASP-8, ICE-like Apoptotic Protease 5, MORT1-associated CED-3 Homolog, MACH, FADD-homologous ICE/CED-3-like Protease, FADD-like ICE, FLICE, Apoptotic Cysteine Protease, Apoptotic Protease Mch-5, CAP4, Caspase-8 Subunit p18, C Antibody
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Catalog numberMBS648140
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PricePlease ask
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Size50ug
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Alternative name1Anti-Caspase-8L (CASP8, Caspase-8, CASP-8, ICE-like Apoptotic Protease 5, MORT1-associated CED-3 Homolog, MACH, FADD-homologous ICE/CED-3-like Protease, FADD-like ICE, FLICE, Apoptotic Cysteine Protease, Apoptotic Protease Mch-5, CAP4, Caspase-8 Subunit p18, C
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Alternative name2Caspase-8L (CASP8, Caspase-8, CASP-8, ICE-like Apoptotic Protease 5, MORT1-associated CED-3 Homolog, MACH, FADD-homologous ICE/CED-3-like Protease, FADD-like ICE, FLICE, Apoptotic Cysteine Protease, Apoptotic Protease Mch-5, CAP4, Caspase-8 Subunit p18, C
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Alternative name3Caspase-8L (CASP8, Caspase-8, CASP-8, ICE-like Apoptotic Protease 5, MORT1-associated CED-3 Homolog, MACH, FADD-homologous ICE/CED-3-like Protease, FADD-like ICE, FLICE, Apoptotic Cysteine Protease, Apoptotic Protease Mch-5, CAP4, Caspase-8 Subunit p18, C
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Alternative name4Caspase-8L
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Alternative name5Anti -Caspase-8L (CASP8, Caspase-8, CASP-8, ICE-like Apoptotic Protease 5, MORT1-associated CED-3 Homolog, MACH, FADD-homologous ICE/CED-3-like Protease, FADD-like ICE, FLICE, Apoptotic Cysteine Protease, Apoptotic Protease Mch-5, CAP4, Caspase-8 Subunit p18, C
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Other namescaspase-8L; Caspase-8; caspase-8; FADD-like ICE; MACH-alpha-1/2/3 protein; apoptotic protease Mch-5; MACH-beta-1/2/3/4 protein; apoptotic cysteine protease; ICE-like apoptotic protease 5; MORT1-associated ced-3 homolog; FADD-homologous ICE/CED-3-like protease; caspase 8, apoptosis-related cysteine protease; caspase 8, apoptosis-related cysteine peptidase; Apoptotic cysteine protease; Apoptotic protease Mch-5; CAP4; FADD-homologous ICE/ced-3-like protease; FADD-like ICE; FLICE; ICE-like apoptotic protease 5; MORT1-associated ced-3 homolog
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Gene nameN/A
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Gene name synonimsN/A
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Other gene namesCASP8; CASP8; CAP4; MACH; MCH5; FLICE; ALPS2B; Casp-8; MCH5; CASP-8; FLICE; MACH
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CategoryAntibodies
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ClonalityPolyclonal
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Immunoglobulin isotypeN/A
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ClonePolyclonal antibody
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Host organismHost: Rabbit; Source: Human
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Species reactivityHuman
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Specificity and cross reactivityRecognizes human caspase-8L.
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Purification methodPurified
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Form AppearanceSupplied as a liquid in PBS, pH 7.4, 0.05% sodium azide.
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ConcentrationN/A
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Storage and shippingStore at 4 degrees Celsius for short term storage.. Aliquot to avoid repeated freezing and thawing. For optimal long term storage, productone should be kept at -20 degrees Celsius. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
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Tested forWestern Blot (WB)
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Descriptionproductone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against. Properly used, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in. Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, they are inexpensive to manufacture and respectively to buy, the time needed for production is considerably shorter. Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions. To obtain more detailed information on productone, please, refer to the full product datasheet.
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AdvisoryIn order to retain the quality and the affinity of productone unchanged, please, avoid cycles of freezing and thawing. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
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PropertiesIf you buy Antibodies supplied by MBS Polyclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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Additional descriptionHuman and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways.
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GeneCys or cysteines ChEMBL54943
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French translationanticorps
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Gene target
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Gene symbolFADD, CASP8, CASP1, CASP9, CASP5, CES2, CARD18, CARD16, CASP4, CASP7
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Short nameCaspase-8L (CASP8, Caspase-8, CASP-8, ICE-like Apoptotic Protease 5, MORT1-associated CED-3 Homolog, MACH, FADD-homologous ICE/CED-3-like Protease, FADD-like ICE, FLICE, Apoptotic Cysteine Protease, Apoptotic Protease Mch-5, CAP4, Caspase-8 Subunit p18, C Antibody
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TechniqueAntibody, antibodies against human proteins, antibodies for
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Alternative namecaspase-8L (caspase 8, apoptosis-related cysteine peptidase, caspase-8, caspase-8, ICE-like Apoptotic Protease 5, MORT1-associated CED-3 Homolog, MACH, Fas (tumor necrosis factor receptor superfamily, member 6) (TNFRSF6)-associated via death domain-homologous ICE/CED-3-like Protease, Fas (tumor necrosis factor receptor superfamily, member 6) (TNFRSF6)-associated via death domain-like ICE, FLICE, Apoptotic Cysteine Protease, Apoptotic Protease Mch-5, CAP4, caspase-8 functionnal sequence p18, C (antibody to-)
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Alternative techniqueantibodies
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Alternative to gene targetFas (TNFRSF6)-associated via death domain, MORT1, FADD and IDBG-62144 and ENSG00000168040 and 8772, identical protein binding, Plasma membranes, Fadd and IDBG-212910 and ENSMUSG00000031077 and 14082, FADD and IDBG-645056 and ENSBTAG00000018274 and 493720
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Gene info
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Identity
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Gene
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Long gene nameFas associated via death domain
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Synonyms gene name
- Fas (TNFRSF6)-associated via death domain
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1999-05-07
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Death effector domain containing
- Death inducing signaling complex
- Ripoptosome
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene namecaspase 8
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Synonyms gene name
- caspase 8, apoptosis-related cysteine protease
- caspase 8, apoptosis-related cysteine peptidase
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Synonyms
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GenBank acession
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Locus
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Discovery year1996-11-11
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Caspases
- Death effector domain containing
- Death inducing signaling complex
- Ripoptosome
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene namecaspase 1
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Synonyms gene
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Synonyms gene name
- caspase 1, apoptosis-related cysteine protease (interleukin 1, beta, convertase)
- caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)
- caspase 1, apoptosis-related cysteine peptidase
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1992-05-07
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Caspases
- Caspase recruitment domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namecaspase 9
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Synonyms gene name
- caspase 9, apoptosis-related cysteine protease
- caspase 9, apoptosis-related cysteine peptidase
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1996-11-11
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Caspases
- Apoptosome
- Caspase recruitment domain containing
- Protein phosphatase 1 regulatory subunits
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namecaspase 5
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Synonyms gene name
- caspase 5, apoptosis-related cysteine protease
- caspase 5, apoptosis-related cysteine peptidase
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Synonyms
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Locus
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Discovery year1996-09-13
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Caspases
- Caspase recruitment domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namecarboxylesterase 2
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Synonyms gene name
- carboxylesterase 2 (intestine, liver)
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Synonyms
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GenBank acession
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Locus
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Discovery year1993-09-30
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Carboxylesterases
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namecaspase recruitment domain family member 18
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Synonyms gene name
- caspase recruitment domain family, member 18
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Synonyms
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GenBank acession
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Locus
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Discovery year2008-09-02
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Caspase recruitment domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namecaspase recruitment domain family member 16
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Synonyms gene name
- caspase recruitment domain family, member 16
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Synonyms
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Locus
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Discovery year2008-09-15
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Entrez gene record
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Pubmed identfication
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Classification
- Caspase recruitment domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namecaspase 4
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Synonyms gene name
- caspase 4, apoptosis-related cysteine protease
- caspase 4, apoptosis-related cysteine peptidase
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Synonyms
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GenBank acession
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Locus
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Discovery year1996-07-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Caspases
- Caspase recruitment domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namecaspase 7
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Synonyms gene name
- caspase 7, apoptosis-related cysteine protease
- caspase 7, apoptosis-related cysteine peptidase
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Synonyms
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GenBank acession
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Locus
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Discovery year1996-07-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Caspases
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Theoretical representations that simulate the behavior or activity of chemical processes or phenomena; includes the use of mathematical equations, computers, and other electronic equipment.
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Tree numbers
- E05.599.495