Calsequestrin Antibody

• Catalog number
  bs-2961R
• Price
  Please ask
• Size
  0.1ml

• Long name
  Calsequestrin Primary Polyclonal Antibody
• Also known as
  Calsequestrin PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  Calsequestrin
• Specificity
  This is a highly specific antibody against Calsequestrin.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Calsequestrin
• Gene ID number
  844
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  The sarcoplasmic reticulum (SR) is, in part, responsible for maintaining the level of intracellular calcium in cardiac and skeletal muscle by storing and releasing calcium. Several intralumenal SR calcium binding proteins have been identified, the most prominent of these is calsequestrin. Calsequstrin is a calcium binding protein known to sequester calcium accumulated in the sarcoplasmic reticulum of muscle cells during relaxation and is found discretely localized to the junctional and corbular (terminal cisternae) SR. Calsequestrin functions to localize calcium near the junctional face of the terminal cisternae from which calcium can be released into the cytosol via the ryanodine receptor. This protein is highly acidic and has a large capacity and moderate to low affinity for calcium.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  CASQ; Calsequestrin 1; Calsequestrin 1 fast twitch skeletal muscle; Calsequestrin skeletal muscle isoform; CASQ 1; PDIB1; Skeletal muscle calsequestrin 1.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Calsequestrin  
• Gene symbol
  CASQ2, CASQ1
• Short name
  Anti-Calsequestrin
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  Calsequestrin Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:1513
• Gene
  CASQ2
• Long gene name
  calsequestrin 2
• Synonyms gene name
  • calsequestrin 2 (cardiac muscle)
• Synonyms
  • PDIB2
• GenBank acession
  • BC022288
• Locus
  1p13.1
• Discovery year
  1992-11-05
• Entrez gene record
  845
• Pubmed identfication
  • 8406504
• RefSeq identity
  • NM_001232
• Classification
  • Protein disulfide isomerases
• VEGA ID
  OTTHUMG00000011970
• Locus Specific Databases
  • LRG_404

Gene info

• Identity
  HGNC:1512
• Gene
  CASQ1
• Long gene name
  calsequestrin 1
• Synonyms gene
  • CASQ
• Synonyms gene name
  • calsequestrin 1 (fast-twitch, skeletal muscle)
• Synonyms
  • PDIB1
• Synonyms name
  • calsequestrin 1, fast-twitch, skeletal muscle
  • calmitine
• GenBank acession
  • S73775
• Locus
  1q23.2
• Discovery year
  1990-08-23
• Entrez gene record
  844
• Pubmed identfication
  • 8406504
  • 2321095
• RefSeq identity
  • NM_001231
• Classification
  • Protein disulfide isomerases
• VEGA ID
  OTTHUMG00000031607

MeSH Data

• Name
  Sequence Analysis, DNA
• Concept
  Scope note: A multistage process that includes cloning, physical mapping, subcloning, determination of the DNA SEQUENCE, and information analysis.
• Tree numbers
  • E05.393.760.700
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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