C17orf53 Antibody

• Catalog number
  bs-9641R
• Price
  Please ask
• Size
  0.1ml

• Long name
  C17orf53 Primary Polyclonal Antibody
• Also known as
  C17orf53 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  C17orf53
• Specificity
  This is a highly specific antibody against C17orf53.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human C17orf53
• Gene ID number
  78995
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  C17orf53 is a 647 amino acid protein that is encoded by a gene mapping to human chromosome 17. Chromosome 17 makes up over 2.5% of the human genome with about 81 million bases encoding over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes. Chromosome 17 is also linked to neurofibromatosis, a condition characterized by neural and epidermal lesions, and dysregulated Schwann cell growth. Alexander disease, Birt-Hogg-Dube syndrome and Canavan disease are also associated with chromosome 17.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  C17orf53; chromosome 17 open reading frame 53; CQ053_HUMAN; FLJ11594; hypothetical protein LOC78995; MGC3130; Uncharacterized protein C17orf53.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  C17orf53  
• Gene symbol
  HROB
• Short name
  Anti-C17orf53
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  C17orf53 Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:28460
• Gene
  HROB
• Long gene name
  homologous recombination factor with OB-fold
• Synonyms gene
  • C17orf53
• Synonyms gene name
  • chromosome 17 open reading frame 53
• Synonyms
  • MGC3130
  • MCM8IP
• GenBank acession
  • AK021656
• Locus
  17q21.31
• Discovery year
  2005-12-15
• Entrez gene record
  78995
• Pubmed identfication
  • 31467087
  • 32528060
• RefSeq identity
  • NM_024032
• VEGA ID
  OTTHUMG00000181808

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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