Betacellulin Recombinant Protein
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Catalog number
40-192
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Price
Please ask
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Size
0.005 mg, 0.02 mg
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About recombinant protein
Betacellulin is an EGF-related polypeptide growth factor that signals through the EGF receptor. It is produced in several tissues, including the pancreas, small intestine, and in certain tumor cells. Betacellulin is a potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells. Human Betacellulin is initially synthesized as a glycosylated 32.0 kDa transmembrane precursor protein, which is processed by proteolytic cleavage to produce the mature sequence. Recombinant human Betacellulin is a 9.0 kDa monomeric protein, containing 80 amino residues, which comprises the mature EGF homologous portion of the Betacellulin protein.
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Other name of the recombinant
Probetacellulin, BTC
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Recombinant in
E. coli
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SEQUENCE
DGNSTRSPET NGLLCGDPEE NCAATTTQSK RKGHFSRCPK QYKHYCIKGR CRFVVAEQTP SCVCDEGYIG ARCERVDLFY
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Activity
The ED50 was determined by the dose - dependent stimulation of the proliferation of murine Balb/3T3 cells is ≤ 0.05 ng/mL, corresponding to a specific activity of ≥ 2 x 107units/mg.
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Keep at
The lyophilized Betacellulin recombinant protein is stable for at least 2 years from date of receipt at -20˚C. Reconstituted Betacellulin is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚C. As with any protein, exposing Betacellulin recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
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Rec PROTEIN GI
4502461
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Accession nr
NP_001720.1
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Pureity
Greater than 98% by SDS-PAGE gel and HPLC analyses.Endotoxin level is less than 0.1 ng per μg (1EU/μg).
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About
This product is for research use only.
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Protein s origin
Human
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Vial
Lyophilized
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NCBI ID
685
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Gene name
betacellulin
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Source
Homo sapiens
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Uniprot
P35070
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Additional source
Recombinants or rec. proteins
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Group
recombinants
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Gene target
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Gene symbol
BTC
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Short name
Betacellulin Recombinant Protein
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Technique
Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. proscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
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Alternative name
Betacellulin Rec. Protein
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Alternative technique
rec
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Gene info
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Identity
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Gene
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Long gene name
betacellulin
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GenBank acession
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Locus
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Discovery year
1994-07-21
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Entrez gene record
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Pubmed identfication
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VEGA ID
MeSH Data
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Name
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Concept
Scope note:
The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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