beta 3 Adrenergic Receptor Antibody

• Catalog number
  bs-1063R
• Price
  Please ask
• Size
  0.1ml

• Long name
  beta 3 Adrenergic Receptor Antibody
• Also known as
  beta 3 Adrenergic Receptor Antibody
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  beta 3 Adrenergic Receptor
• Specificity
  This is a highly specific antibody against beta 3 Adrenergic Receptor.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  345-395/400
• Subcellular location
  Cytoplasm
• Source
  KLH conjugated synthetic peptide derived from mouse ADRB3
• Gene ID number
  11556
• Swiss Prot
  P25962
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. Beta-3 is involved in the regulation of lipolysis and thermogenesis.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  Adrb-3; Beta-3 adrenergic receptor; Beta-3 adrenoreceptor; Beta-3 adrenoceptor; Adrb3; Adrb3r; B3bar
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Description
  The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
• French translation
  anticorps

• Gene target
  beta   Adrenergic   Receptor  
• Gene symbol
  ADRB3, GRK3
• Short name
  Anti-beta 3 Adrenergic Receptor
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  beta 3 Adrenergic Receptor Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:288
• Gene
  ADRB3
• Long gene name
  adrenoceptor beta 3
• Synonyms gene name
  • adrenergic, beta-3-, receptor
• GenBank acession
  • AY487247
• Locus
  8p11.23
• Discovery year
  1993-10-04
• Entrez gene record
  155
• Pubmed identfication
  • 7898940
  • 15123695
• RefSeq identity
  • NM_000025
• Classification
  • Adrenoceptors
• VEGA ID
  OTTHUMG00000164028

Gene info

• Identity
  HGNC:290
• Gene
  GRK3
• Long gene name
  G protein-coupled receptor kinase 3
• Synonyms gene
  • ADRBK2
• Synonyms gene name
  • adrenergic, beta, receptor kinase 2
• Synonyms
  • BARK2
• GenBank acession
  • X69117
• Locus
  22q12.1
• Discovery year
  1992-03-25
• Entrez gene record
  157
• Pubmed identfication
  • 7695743
• RefSeq identity
  • NM_005160
• Classification
  • AGC family kinases
  • Pleckstrin homology domain containing
• VEGA ID
  OTTHUMG00000150280

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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