BCA-1/BLC (CXCL13), human recombinant
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Catalog number4001-20
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Price:
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Size20 ug
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SynonymsB cell Attracting Chemokine-1, CXCL13, BLC (mouse), BLR1 Ligand
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Alternative_namesB cell Attracting Chemokine-1, CXCL13, BLC (mouse), BLR1 Ligand, Angie, B lymphocyte chemoattractant, CXC chemokine BLC, Small-inducible cytokine B13
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DescriptionA cytokine selectively chemotactic for B cells
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RecombinantYes
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SourceE. coli
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Purity by SDS PAGE≥95%
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AssaySDS-PAGE
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Purity≥95%
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Biological activityDetermined by its ability to chemoattract human B cells using a concentration range of 1.0-10 ng/ml.
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Results1.0-10 ng/ml.
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Molecular Weight10.1 kDa
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Storage Temp-20°C
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ShippingGel pack
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Shelf Life12 months
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AppearanceLyophilized protein
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Physical form descriptionSterile filtered and lyophilized from 10 mM TFA
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Reconstitution InstructionsCentrifuge the vial prior to opening. Reconstitute in H₂O to a concentration of 0.1-1 mg/ml. The solution can then be diluted into other aqueous buffers or store at 4°C for 1 week or -20°C for future use.
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Background InformationHuman BCA-1 (B Cell-Attracting chemokine 1), also known as BLC or CXCL13, is a recently identified new CXC chemokines. Human BCA-1 is a highly effective attractant for human blood B lymphocytes, but was inactive on freshly isolated or IL-2 stimulated T lymphocytes, monocytes and neutrophils. The human BCA-1 is a 10.1 kDa protein containing 85 amino acid residues.
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HandlingCentrifuge the vial prior to opening.
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UsageFor Research Use Only! Not to be used in humans
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PropertiesHuman proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Additional sourceRecombinants or rec. proteins
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Grouprecombinants
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Gene target
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Gene symbolCXCL13, BLNK, IGHVII-1-1, MIR1-1, TRUND-NNN8-1, TRUND-NNN7-1, IGKV1OR2-1, MIR1289-1, MIR101-1, MIR16-1
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Short nameBCA-1/BLC (CXCL13), recombinant
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TechniqueRecombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
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SpeciesHuman, Humans
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Alternative nameBicinchoninic acid-1/BLC (chemokine (C-X-C motif) ligand 13), H. sapiens Rec.
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Alternative techniquerec
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Alternative to gene targetchemokine (C-X-C motif) ligand 13, ANGIE and ANGIE2 and BCA-1 and BCA1 and BLC and BLR1L and SCYB13, CXCL13 and IDBG-25774 and ENSG00000156234 and 10563, CXCR3 chemokine receptor binding, Extracellular, Cxcl13 and IDBG-181227 and ENSMUSG00000023078 and 55985, CXCL13 and IDBG-643139 and ENSBTAG00000008479 and 511674
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Gene info
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Identity
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Gene
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Long gene nameC-X-C motif chemokine ligand 13
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Synonyms gene
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Synonyms gene name
- small inducible cytokine B subfamily (Cys-X-Cys motif), member 13 (B-cell chemoattractant)
- chemokine (C-X-C motif) ligand 13
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2000-09-05
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Entrez gene record
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Pubmed identfication
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Classification
- Chemokine ligands
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameB cell linker
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2001-07-16
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- SH2 domain containing
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene nameimmunoglobulin heavy variable (II)-1-1 (pseudogene)
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Synonyms gene name
- immunoglobulin heavy variable (II)-1-1
- immunoglobulin heavy variable (II)-1-1 pseudogene
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Synonyms
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GenBank acession
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Locus
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Discovery year2000-04-17
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Entrez gene record
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RefSeq identity
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Classification
- Immunoglobulin heavy locus at 14q32.33
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namemicroRNA 1-1
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Synonyms gene
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Synonyms
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Locus
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Discovery year2004-04-23
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Entrez gene record
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RefSeq identity
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Classification
- MicroRNA MIR1/206 family
Gene info
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Identity
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Gene
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Long gene nametRNA-undetermined (NNN) 8-1
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Synonyms gene name
- transfer RNA-undetermined (NNN) 8-1
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GenBank acession
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Locus
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Discovery year2014-06-20
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Entrez gene record
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Pubmed identfication
Gene info
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Identity
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Gene
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Long gene nametRNA-undetermined (NNN) 7-1
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Synonyms gene name
- transfer RNA-undetermined (NNN) 7-1
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GenBank acession
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Locus
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Discovery year2014-06-20
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Entrez gene record
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Pubmed identfication
Gene info
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Identity
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Gene
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Long gene nameimmunoglobulin kappa variable 1/OR2-1 (pseudogene)
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Synonyms gene
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Synonyms gene name
- immunoglobulin kappa variable 1/OR-1
- immunoglobulin kappa variable 1/OR-1 pseudogene
- immunoglobulin kappa variable 1/OR-1 (pseudogene)
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Synonyms
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GenBank acession
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Locus
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Discovery year2000-04-18
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Entrez gene record
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Pubmed identfication
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Classification
- Immunoglobulin kappa (IGK) orphons
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namemicroRNA 1289-1
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Synonyms gene
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Synonyms
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Locus
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Discovery year2008-11-03
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Entrez gene record
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RefSeq identity
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Classification
- MicroRNA MIR1289 family
Gene info
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Identity
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Gene
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Long gene namemicroRNA 101-1
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Synonyms gene
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Synonyms
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Locus
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Discovery year2004-04-23
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Entrez gene record
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RefSeq identity
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Classification
- MicroRNA MIR101 family
Gene info
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Identity
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Gene
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Long gene namemicroRNA 16-1
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Synonyms gene
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Synonyms
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Locus
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Discovery year2004-04-23
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Entrez gene record
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RefSeq identity
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Classification
- MicroRNA MIR15/16 family
MeSH Data
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Name
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ConceptScope note: The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data