BARD1 Antibody

• Catalog number
  bs-4291R
• Price
  Please ask
• Size
  0.1ml

• Long name
  BARD1 Primary Polyclonal Antibody
• Also known as
  BARD1 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  BARD1
• Specificity
  This is a highly specific antibody against BARD1.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  120-170/777
• Subcellular location
  Nucleus
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human BARD1
• Gene ID number
  580
• Swiss Prot
  Q99728
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Probable E3 ubiquitin-protein ligase. The BRCA1-BARD1 heterodimer specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain genomic stability. Plays a central role in the control of the cell cycle in response to DNA damage. Acts by mediating ubiquitin E3 ligase activity that is required for its tumor suppressor function. Also forms a heterodimer with CSTF1/CSTF-50 to modulate mRNA processing and RNAP II stability by inhibiting pre-mRNA 3' cleavage.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  BRCA1-associated RING domain protein 1; BARD-1; BARD1
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  BARD1  
• Gene symbol
  BARD1
• Short name
  Anti-BARD1
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  BARD1 Polyclonal Antibody
• Alternative technique
  antibodies
• Alternative to gene target
  BRCA1 associated RING domain 1, BARD1 and IDBG-80113 and ENSG00000138376 and 580, protein heterodimerization activity, nuclei, Bard1 and IDBG-164443 and ENSMUSG00000026196 and 12021, BARD1 and IDBG-643630 and ENSBTAG00000033690 and 530961

Gene info

• Identity
  HGNC:952
• Gene
  BARD1
• Long gene name
  BRCA1 associated RING domain 1
• Locus
  2q35
• Discovery year
  1998-08-05
• Entrez gene record
  580
• Pubmed identfication
  • 8944023
  • 9425226
  • 15159397
• RefSeq identity
  • NM_000465
• Classification
  • Ankyrin repeat domain containing
  • Ring finger proteins
  • BRCA1 B complex
• VEGA ID
  OTTHUMG00000133016
• Locus Specific Databases
  • LRG_297

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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