BACE1 (Ser498) Antibody
#
-
Catalog numberbs-5215R
-
Price:
-
Size0.1ml
-
-
Long nameBACE1 (Ser498) Primary Polyclonal Antibody
-
Also known asBACE1 (Ser498) PAb
-
CategoryPrimary Antibodies
-
ConjugationUnconjugated
-
Target AntigenBACE1 Ser498
-
SpecificityThis is a highly specific antibody against BACE1 Ser498.
-
Modification sPhosphorylation
-
Modification site sSer498
-
ClonalityPolyclonal antibody
-
Clone numberPolyclonal antibody
-
Concentration1ug per 1ul
-
SourceKLH conjugated synthetic phosphopeptide derived from human BACE1 around the phosphorylation site of Ser498
-
Gene ID number23621
-
Tested ApplicationsWB, IHC-P, IF(IHC-P)
-
Recommended dilutionsWB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
-
Cross reactivityHuman, Mouse, Rat
-
Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
-
Background of the target antigenCerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein(APP) by two proteases, one of which is the protein encoded by this gene. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi. Multiple transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq].
-
Purification methodThis antibody was purified via Protein A.
-
Storage conditionsKeep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
-
Synonym namesBACE1 Ser498; BACE1 S498; p-BACE1 Ser498; p-BACE1 Se498; APP beta secretase; Asp 2; ASP2; Aspartyl protease 2; BACE 1; BACE; Beta secretase 1; Beta secretase; Beta site amyloid beta A4 precursor protein cleaving enzyme; Beta site amyloid precursor protein cleaving enzyme 1; Beta site amyloid precursor protein cleaving enzyme; Beta site APP cleaving enzyme 1; Beta site APP cleaving enzyme; FLJ90568; HSPC104; KIAA1149; Memapsin-2; Memapsin 2; Memapsin2; Membrane associated aspartic protease 2; Transmembrane aspartic proteinase Asp2; BACE1_HUMAN; Beta-secretase 1; Beta-site amyloid precursor protein cleaving enzyme 1; Beta-site APP cleaving enzyme 1; Membrane-associated aspartic protease 2.
-
PropertiesIf you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
French translationanticorps
-
Gene target
-
Gene symbolBACE1, BACE1-AS
-
Short nameAnti-BACE1 Ser498
-
TechniqueAntibody, antibodies against human proteins, antibodies for
-
HostRabbit (Oryctolagus cuniculus)
-
IsotypeImmunoglobulin G (IgG)
-
Alternative nameBACE1 (Ser498) Polyclonal Antibody
-
Alternative techniqueantibodies
-
Gene info
-
Identity
-
Gene
-
Long gene namebeta-secretase 1
-
Synonyms gene
-
Synonyms gene name
- beta-site APP-cleaving enzyme
- beta-site APP-cleaving enzyme 1
-
GenBank acession
-
Locus
-
Discovery year1999-10-29
-
Entrez gene record
-
Pubmed identfication
-
Classification
- Peptidase family A1
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nameBACE1 antisense RNA
-
Synonyms gene
-
Synonyms gene name
- BACE1 antisense RNA (non-protein coding)
-
Synonyms
-
Synonyms name
-
Locus
-
Discovery year2009-07-15
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Antisense RNAs
-
VEGA ID
MeSH Data
-
Name
-
ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data