Azidothymidine

Azidothymidine is available 4 times from Biovision labs

B1113-10 | Azidothymidinesize: 2X10 mg | 316.99 USD

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B1113-50 | Azidothymidinesize: 50 mg | 424.54 USD

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B1113-50 | Azidothymidine for cell activationsize: 50 mg | 333.97 USD

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B1113-10 | Azidothymidine for cell activationsize: 10 mg | 136.98 USD

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  • Description
    Azidothymidine is a nucleoside reverse transcriptase inhibitor that, following triphosphorylation by thymidine kinase, potently blocks replication of HIV (EC₅₀ = 3 nM) with low cytotoxicity (CC₅₀ > 5 μM). Displays 100-fold selectivity for HIV reverse transcriptase over DNA polymerase α. Suppresses HIV-1 replication and enhances cell viability in HIV-1 infected T cells. Antiretroviral agent. Also decreases CRISPR-mediated homology directed repair (HDR) efficiency.
  • Peptide sequence
    N/A
  • CAS number
    30516-87-1
  • Molecular weight
    267.24
  • Category
    Biochemicals
  • Other name
    3'-Azido-3'-deoxythymidine; AZT; Zidovudine
  • Molecular formula
    C₁₀H₁₃N₅O₄
  • Physical appearance
    White solid
  • Supplied with
    N/A
  • Is this a salt?
    No
  • Is it cell-permeable?
    Yes
  • Purification
    ≥98% by HPLC
  • Reconstitute instructions
    DMSO (>25 mg/ml) or H2O (>10 mg/ml)
  • Storage condition
    -20°C
  • Shipping condition
    gel pack
  • Maximum time for storage
    36 months
  • Storage instructions
    Protect from air and moisture
  • Alternate Name/Synonyms
    3'-Azido-3'-deoxythymidine; AZT; Zidovudine
  • Appearance
    White solid
  • Formulation
    N/A
  • CAS Number
    30516-87-1
  • Molecular Formula
    C₁₀H₁₃N₅O₄
  • Molecular Weight
    267.24
  • Purity
    ≥98% by HPLC
  • Solubility/Reconstitution Instructions
    DMSO (>25 mg/ml) or H2O (>10 mg/ml)
  • Handling
    Protect from air and moisture
  • Tagline
    A nucleoside reverse transcriptase inhibitor and homology directed repair (HDR) blocker
  • Storage Temp.
    -20°C
  • Shipping Conditions
    gel pack
  • Shelf Life
    36 months
  • MDL Number
    MFCD00006536
  • PubChem CID
    35370
  • Alternative technique
    blots
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