Aurora-C Antibody (AURKC)

• Catalog number
  F50012-0.08ML
• Price
  Please ask
• Size
  0.08 ml

• Category
  Antibody
• Concentration
  In 1X PBS, pH 7.4, with 0.09% sodium azide
• Form
  Purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  Aurora-C (AURKC)
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, ELISA
• Recommended dilutions
  Western blot: 1:1000
• Notes
  Titration of the Aurora-C antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This Aurora-C antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  Q9UQB9
• Purity
  Purified
• Description
  Chromosomal segregation during mitosis as well as meiosis is regulated by kinases and phosphatases. The Aurora kinases, members of the Ser/Thr protein kinase family, associate with microtubules during chromosome movement and segregation. Aurora kinase C may play a part in organizing microtubules in relation to the function of the centrosome/spindle pole during mitosis. This protein is localized to centrosome from anaphase to cytokinesis. Expression is limited to testis in normal cells. Elevated expression levels are seen only in a subset of cancer cells such as HepG2, HuH7 and HeLa cells. Aurora-C expression is maximum at M phase.
• Immunogen
  A portion of amino acids 1-30 from the human protein was used as the immunogen for this Aurora-C antibody.
• Storage
  Aliquot the Aurora-C antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Aurora-C   AURKC  
• Gene symbol
  AURKC
• Short name
  Anti-Aurora-C (AURKC)
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit Ig
• Alternative name
  Antibodies to Aurora-C (AURKC)
• Alternative technique
  antibodies
• Alternative to gene target
  aurora kinase C, AIE2 and AIK3 and ARK3 and AurC and aurora-C and SPGF5 and STK13, AURKC and IDBG-71872 and ENSG00000105146 and 6795, transferase activity, nuclei, Aurkc and IDBG-141309 and ENSMUSG00000070837 and 20871

Gene info

• Identity
  HGNC:11391
• Gene
  AURKC
• Long gene name
  aurora kinase C
• Synonyms gene
  • STK13
• Synonyms gene name
  • serine/threonine kinase 13 (aurora/IPL1-like)
• Synonyms
  • AurC
  • ARK3
• Locus
  19q13.43
• Discovery year
  1998-05-13
• Entrez gene record
  6795
• Pubmed identfication
  • 9799611
• RefSeq identity
  • NM_003160
• VEGA ID
  OTTHUMG00000183106

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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