AT 101 for cell activation

AT 101 for cell activation is available 2 times from Biovision labs

2380-25 | AT-101 for cell activationsize: 25 mg | 596.18 USD

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2380-5 | AT-101 for cell activationsize: 5 mg | 192.85 USD

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  • Description
    AT-101 is the R-(-) enantiomer of Gossypol that acts as an inhibitor of the antiapoptotic Bcl proteins (Bcl-2, Bcl-XL, Bcl-W, and Mcl-1) and an inducer of the pro-apoptotic proteins noxa and puma. It induces apoptosis in drug-resistant multiple myeloma cell lines. Apoptosis is activated by the mitochondrial pathway.
  • Peptide sequence
    N/A
  • CAS number
    90141-22-3
  • Molecular weight
    518.56
  • Category
    Biochemicals
  • Other name
    (-)-1,1',6,6',7,7'-Hexahydroxy-3,3'-dim­ethyl-5,5'-bis(1-methylethyl)-[2,2'-binaphthalene]-8­,8'-dicarboxaldehyde; (R)-Gossypol
  • Molecular formula
    C₃₀H₃₀O₈
  • Physical appearance
    Light brown solid
  • Supplied with
    N/A
  • Is this a salt?
    No
  • Is it cell-permeable?
    Yes
  • Purification
    ≥98% by TLC
  • Reconstitute instructions
    DMSO (~50 mg/ml) or EtOH (~50 mg/ml)
  • Storage condition
    -20 ̊C
  • Shipping condition
    gel pack
  • Maximum time for storage
    36 months
  • Storage instructions
    Protect from light and air
  • Additional description
    For cells, cell lines and tissues in culture till half confluency.
  • Gene target
  • Short name
    AT-101 for activation
  • Technique
    activation
  • Alternative name
    AT-101 to measure cellular activation
  • Tissue
    cell
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