ASPH/Aspartate beta hydroxylase Antibody, ALEXA FLUOR 350
-
Catalog numberbs-12137R-A350
-
PricePlease ask
-
Size100ul
-
-
Long nameASPH/Aspartate beta hydroxylase Antibody, ALEXA FLUOR 350 Conjugated
-
Also known asAnti-ASPH/Aspartate beta hydroxylase PAb ALEXA FLUOR 350
-
CategoryConjugated Primary Antibodies
-
Conjugated withALEXA FLUOR® 350
-
Host OrganismRabbit (Oryctolagus cuniculus)
-
Target AntigenASPH/Aspartate beta hydroxylase
-
SpecificityThis is a highly specific antibody against ASPH/Aspartate beta hydroxylase.
-
ModificationUnmodified
-
Modification SiteNone
-
ClonalityPolyclonal
-
ClonePolyclonal antibody
-
Concentration1ug per 1ul
-
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ASPH/Aspartate beta hydroxylase
-
Tested applicationsIF(IHC-P)
-
Recommended dilutionsIF(IHC-P)(1:50-200)
-
CrossreactivityHuman, Mouse, Rat
-
Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
-
Background of the antigenAspartyl/asparaginyl beta-hydroxylase (ASPH) is a widely-expressed type II membrane protein involved in calcium homeostasis. Located in the endoplasmic reticulum, ASPH specifically hydroxylates an Asp or Asn residue in the epidermal growth factor-like (EGF) domains of several proteins, using iron as a cofactor. The ASPH gene encodes 3 proteins, ASPH, Junctin, and Junctate (or Humbug), that differ significantly in their C-terminal domains. These ASPH gene products are expressed as five transcript variants that differ by their roles in calcium storage and release, hydroxylation capabilities, and tissue specificity. While all ASPH variants are expressed in skeletal muscle, only some are detected in heart, brain, pancreas, placenta, lung, liver, and kidney tissues. In the lumen of the endoplasmic reticulum, ASPH can be processed into two different forms.
-
PurificationPurified by Protein A.
-
Storage conditionsStore this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
-
Excitation emission343nm/442nm
-
SynonymsASP beta hydroxylase; Aspartyl/asparaginyl beta hydroxylase; ASPH; BAH; CASQ2BP1; HAAH; JCTN; junctin; Peptide aspartate beta dioxygenase; ASPH_HUMAN.
-
PropertiesFor facs or microscopy Alexa 1 conjugate. Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
ConjugationAlexa Fluor, ALEXA FLUOR 350
-
French translationanticorps
-
Gene target
-
Gene symbolASPH
-
Short nameAnti-ASPH/Aspartate beta hydroxylase
-
TechniqueAntibody, antibodies against human proteins, antibodies for
-
IsotypeImmunoglobulin G (IgG)
-
LabelALEXA FLUOR 350
-
Alternative nameASPH/Aspartate beta hydroxylase Antibody, ALEXA FLUOR 350
-
Alternative techniqueantibodies
-
Gene info
-
Identity
-
Gene
-
Long gene nameaspartate beta-hydroxylase
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year1995-06-13
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
VEGA ID
MeSH Data
-
Name
-
ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data