ASCL1 Antibody (Achaete-scute homolog 1)

#

• Catalog number
  F47525-0.08ML
• Price:

  Please ask

  Ask for price
• Size
  0.08 ml

# #

• Category
  Antibody
• Concentration
  In 1X PBS, pH 7.4, with 0.09% sodium azide
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  ASCL1 (Achaete-scute homolog 1)
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, ELISA
• Recommended dilutions
  Western blot: 1:1000
• Notes
  Titration of the ASCL1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This ASCL1 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  P50553
• Purity
  Antigen affinity
• Description
  This gene encodes 'Achaete scute complex homolog like 1' (ASCL1) or 'Mammalian achaete scute complex homolog 1' (MASH1), a member of the basic helix-loop-helix (BHLH) family of transcription factors. The protein activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. This protein plays a role in the neuronal commitment and differentiation and in the generation of olfactory and autonomic neurons. Mutations in this gene may contribute to the congenital central hypoventilation syndrome (CCHS) phenotype in rare cases.
• Immunogen
  A portion of amino acids 63-90 from the human protein was used as the immunogen for this MASH1 / ASCL1 antibody.
• Storage
  Aliquot the ASCL1 antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

#

• Gene target
  ASCL1   Achaete-scute   homolog  
• Gene symbol
  ASCL1
• Short name
  Anti-ASCL1 (Achaete-scute homolog 1)
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit Ig
• Alternative name
  Antibodies to ASCL1 (Achaete-scute homolog 1)
• Alternative technique
  antibodies
• Alternative to gene target
  achaete-scute complex homolog 1 (Drosophila), ASH1 and bHLHa46 and HASH1 and MASH1, ASCL1 and IDBG-53767 and ENSG00000139352 and 429, E-box binding, nuclei, Ascl1 and IDBG-182849 and ENSMUSG00000020052 and 17172, ASCL1 and IDBG-648540 and ENSBTAG00000016227 and 540473

Gene info

• Identity
  HGNC:738
• Gene
  ASCL1
• Long gene name
  achaete-scute family bHLH transcription factor 1
• Synonyms gene name
  • achaete-scute complex (Drosophila) homolog-like 1
  • achaete-scute complex-like 1 (Drosophila)
  • achaete-scute complex homolog 1 (Drosophila)
• Synonyms
  • ASH1
  • HASH1
  • bHLHa46
• GenBank acession
  • L08424
• Locus
  12q23.2
• Discovery year
  1993-12-09
• Entrez gene record
  429
• Pubmed identfication
  • 8390674
• Classification
  • Basic helix-loop-helix proteins
• VEGA ID
  OTTHUMG00000169967

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Similar products