Amyloid beta Antibody

• Catalog number
  F49577-0.4ML
• Price
  Please ask
• Size
  0.4 ml

• Category
  Antibody
• Concentration
  In 1X PBS, pH 7.4, with 0.09% sodium azide
• Form
  Purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  Amyloid beta
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, ELISA
• Recommended dilutions
  Western blot: 1:1000
• Notes
  Titration of the Amyloid beta antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This Amyloid beta antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  P05067
• Purity
  Purified
• Description
  APP is a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Aβ is the main component of amyloid plaques (extracellular deposits found in the brains of patients with Alzheimer's disease).[19] Similar plaques appear in some variants of Lewy body dementia and in inclusion body myositis (a muscle disease), while Aβ can also form the aggregates that coat cerebral blood vessels in cerebral amyloid angiopathy. [Wiki]
• Immunogen
  A portion of amino acids 736-770 from the human protein was used as the immunogen for this Amyloid beta antibody.
• Storage
  Aliquot the Amyloid beta antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Amyloid   beta  
• Gene symbol
  APLP1, APLP2
• Short name
  Anti-Amyloid beta
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit Ig
• Alternative name
  Antibodies to Amyloid beta
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:597
• Gene
  APLP1
• Long gene name
  amyloid beta precursor like protein 1
• Synonyms gene name
  • amyloid beta (A4) precursor-like protein 1
• Synonyms
  • APLP
• Synonyms name
  • amyloid-like protein 1
  • amyloid precursor-like protein 1
• GenBank acession
  • U48437
• Locus
  19q13.12
• Discovery year
  1992-06-18
• Entrez gene record
  333
• Pubmed identfication
  • 8432545
• RefSeq identity
  • NM_001024807
• VEGA ID
  OTTHUMG00000180692

Gene info

• Identity
  HGNC:598
• Gene
  APLP2
• Long gene name
  amyloid beta precursor like protein 2
• Synonyms gene
  • APPL2
• Synonyms gene name
  • amyloid beta (A4) precursor-like protein 2
• Synonyms
  • APPH
• GenBank acession
  • L19597
• Locus
  11q24.3
• Discovery year
  1993-06-23
• Entrez gene record
  334
• Pubmed identfication
  • 10702673
• RefSeq identity
  • NM_001642
• VEGA ID
  OTTHUMG00000165767

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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