anti-WSB1 Antibody
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Catalog number8161
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Price:
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Size0.02 mg, 0.1 mg
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Gene infoThe WD repeat and SOCS box-containing 1 (WSB1, also known as SWIP1), is a member of the WD-protein subfamily (1). It contains six WD-repeats spanning most of the protein and an SOCS box in the C-terminus and expressed as multiple alternatively spliced isoforms (1,2). WSB1 is thought to function as part of an SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex that mediates the ubiquitination and proteasomal degradation of target proteins, such as DIO2 (3). Overexpression of WSB1 is implicated in pancreatic cancer progression, suggesting a role for WSB1 in carcinogenesis (4,5).
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Gene namesWD repeat and SOCS box containing 1, SOCS box-containing WD protein SWiP-1, SWIP1, WD repeat and SOCS box-containing protein 1, WSB-1
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Antibodie s labelunlabelled serum
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PurityWSB1 antibody is affinity chromatography purified via peptide column.
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Ab raised inRabbit
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TypePolyclonal
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ImmunoglobulinIgG
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Spicific toWSB1 antibody is human specific.
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AntigenWSB1 antibody was made against a 16 amino acid peptide near the amino terminus of human WSB1.
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Immuno applicationELISA, Western Blot, immuno-histo-chemistry, immuno fluorescence
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Antibody adviceWSB1 antibody can be used for detection of WSB1 by Western blot at 1 - 2 ug/mL. Antibody can also be used for immunohistochemistry starting at 5 ug/mL. For immunofluorescence start at 20 ug/mL.
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Suspention pH azideWSB1 antibody is supplied in PBS containing 0.02% sodium azide.
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Keep atWSB1 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year.
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Works withHuman
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Omim nr18677720
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Ncbi nrNP_056441
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KDaPredicted: 46 kDa Observed: 46 kDa
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Vial with antibodyin solution
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Quantity per ml1 mg/mL
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NCBI GENE nr26118
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GENE symbolWSB1
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Antigene nameWD repeat and SOCS box containing 1
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Sourcehomo sapiens
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Protein nrQ9Y6I7
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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PropertiesIf you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolWSB1
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Short nameanti-WSB1 Antibody
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TechniqueAntibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
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Alternative nameAntibody toWSB1 (antibody to-)
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene nameWD repeat and SOCS box containing 1
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Synonyms gene name
- WD repeat and SOCS box-containing 1
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Synonyms
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GenBank acession
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Locus
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Discovery year2004-02-20
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- WD repeat domain containing
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data