anti-WAC Antibody
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Catalog number7293
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PricePlease ask
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Size0.02 mg, 0.1 mg
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Gene infoWAC Antibody: The WW domain containing adaptor with coiled-coil protein (WAC) contains a WW domain that mediates protein-protein interactions and colocalizes with RNA splicing factor SC35. Further studies have indicated that WAC is a functional partner of the RNF20/40 complex that ubiquitinates Histone H2B, and that WAC regulates H2B ubiquitination. WAC targets RNF20/40 to associate with RNA polymerase II complex for H2B ubiquitination at active transcription sites. WAC-dependent transcription is also important for cell-cycle checkpoint activation in response to genotoxic stress.
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Gene namesWAC Antibody: Wwp4, BM-016, PRO1741, KIAA1844, WW domain-containing adapter protein with coiled-coil
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Antibodie s labelunlabelled serum
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PurityWAC Antibody is affinity chromatography purified via peptide column.
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Ab raised inRabbit
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TypePolyclonal
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ImmunoglobulinIgG
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Spicific toAt least two isoforms of WAC are known to exist; this antibody will detect the larger isoform.
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AntigenWAC antibody was made against a 19 amino acid peptide near the center of human WAC .
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Immuno applicationELISA, Western Blot, immuno-histo-chemistry, immuno fluorescence
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Antibody adviceWAC Antibody can be used for detection of WAC by Western blot at 1 ug/mL.
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Suspention pH azideWAC Antibody is supplied in PBS containing 0.02% sodium azide.
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Keep atWAC antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year.
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Works withHuman, Mouse, Rat
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Omim nr18379328
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Ncbi nrNP_057712
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KDaPredicted: 71 kDa Observed: 75 kDa
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Vial with antibodyin solution
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Quantity per ml1 mg/mL
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NCBI GENE nr51322
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GENE symbolWAC
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Antigene nameWW domain containing adaptor with coiled-coil
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Sourcehomo sapiens
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Protein nrQ9BTA9
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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PropertiesIf you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolWAC-AS1, WAC
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Short nameanti-WAC Antibody
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TechniqueAntibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
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Alternative nameAntibody toWAC (antibody to-)
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene nameWAC antisense RNA 1 (head to head)
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Locus
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Discovery year2012-11-06
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Entrez gene record
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Pubmed identfication
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Classification
- Antisense RNAs
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameWW domain containing adaptor with coiled-coil
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Synonyms gene name
- WW domain-containing adaptor with coiled coil
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Synonyms
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GenBank acession
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Locus
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Discovery year2004-01-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data