anti-TYRO3 Antibody [1C10E8 / 9A3F2]
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Catalog number
32-233
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Price
Please ask
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Size
0.1 mg
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Gene info
Tyrosine-protein kinase (TYRO3) belongs to the Tyr protein kinase family (AXL/UFO subfamily). The UFO family of receptor tyrosine kinases is comprised of subfamily members Rse(also referred to as Tyro3 or Sky) and UFO (also called Tyro7 or Axl). Two distinct isoforms of Rse, designated Brt and Etk-2, have been described. Brt differs from Rse at its C-terminus, but more importantly lacks the N-terminal 31 amino acid signal peptide sequence present in Rse, which is replaced by a 27 amino acid Brt-specific sequence. It has been suggested that as a result of this alternative splicing event, Brt resides in the cytoplasm, unlike Rse which is expressed on the cell surface. Ekt-2 also lacks an N-terminal signal peptide which is substituted with a 45 amino acid Ekt-2-specific sequence. Protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation.
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Gene names
BYK, DTK, RSE, SKY, TIF, Tyrosine-protein kinase BYKBYK, Dtk, Sky, Tif
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Antibodie s label
unlabelled serum
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Ab raised in
Mouse
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Type
Monoclonal
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Monoclonal
1C10E8 / 9A3F2
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Immunoglobulin
IgG1
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Antigen
Ni-NTA purified truncated recombinant TYRO3 expressed in E. Coli strain BL21 (DE3).
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Immuno application
ELISA, Western Blot, immuno fluorescence
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Antibody advice
Western Blot:1:500 - 1:2,000 IF:1:50 - 1:200ELISA:Propose dilution 1:10,000.Determining optimal working dilutions by titration test.
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Suspention pH azide
Ascitic fluid containing 0.03% sodium azide.
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Keep at
TYRO3 monoclonal antibody can be stored at -20 grades C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Works with
Human
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Omim nr
1717829
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Ncbi nr
Q06418
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NCBI GENE nr
7301
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GENE symbol
TYRO3
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Antigene name
TYRO3 protein tyrosine kinase
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Source
Homo sapiens
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Protein nr
Q06418
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Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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Properties
If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translation
anticorps
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Gene target
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Gene symbol
TYRO3
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Short name
anti-TYRO3 Antibody [1C10E8 / 9A3F2]
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Technique
Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
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Alternative name
Antibody toTYRO3 (antibody to-) [1C10E8 / 9A3F2]
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Alternative technique
antibodies
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Alternative to gene target
TYRO3 protein tyrosine kinase, BYK and Dtk and RSE and Sky and Tif, TYRO3 and IDBG-7206 and ENSG00000092445 and 7301, transferase activity, nuclei, Tyro3 and IDBG-199993 and ENSMUSG00000027298 and 22174, TYRO3 and IDBG-646302 and ENSBTAG00000001694 and 788224
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Gene info
MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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