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Gene info
TRIM30 Antibody: TRIM30 belongs to a family of the tripartite motif (TRIM) proteins involved in the regulation of cell proliferation, differentiation, development, oncogenesis, apoptosis and antiviral responses. The TRIM protein family is an expanding family of RING ('really interesting new gene') proteins, also known as RBCC proteins as they contain an RBCC motif, which comprises a RING domain, one or two B-boxes and a predicted coiled-coil region. Studies have shown that some TRIM family members are critical to innate immunity; TRIM5, TRIM19 and TRIM25, for example, have been shown to restrict viral infection. A recent study shows that TRIM30 functions as a negative modulator of the TLR signaling pathway, by targeting TAB2 and TAB3, and contributes to the inhibition of TLR-mediated NF-kB activation. The importance of TRIM30 in the attenuation or termination of NF-kB activation suggests that targeting of TAB2 and TAB3 by TRIM30a; may be a mechanism for modulating many types of immune responses.
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Gene names
TRIM30 Antibody: Rpt1, Rpt-1, Trim30, Rpt1, Tripartite motif-containing protein 30A, Down regulatory protein of interleukin-2 receptor
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Antibodie s label
unlabelled serum
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Purity
TRIM30 Antibody is affinity chromatography purified via peptide column.
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Ab raised in
Rabbit
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Type
Polyclonal
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Immunoglobulin
IgG
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Antigen
TRIM30 antibody was made against a 16 amino acid synthetic peptide near the carboxy terminus of the mouse TRIM30.
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Immuno application
ELISA, Western Blot, immuno-histo-chemistry, immuno fluorescence
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Antibody advice
TRIM30 antibody can be used for detection of TRIM30 by Western blot at 1 ug/mL. Antibody can also be used for immunohistochemistry starting at 10 ug/mL. For immunofluorescence start at 20 ug/mL.
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Suspention pH azide
TRIM30 Antibody is supplied in PBS containing 0.02% sodium azide.
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Keep at
TRIM30 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Works with
Mouse
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Omim nr
125347379
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Ncbi nr
NP_033125
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Vial with antibody
in solution
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Quantity per ml
1 mg/mL
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NCBI GENE nr
20128
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GENE symbol
Trim30
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Antigene name
tripartite motif-containing 30
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Source
Mus musculus
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Protein nr
P15533
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Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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Properties
If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translation
anticorps
