anti-TMEM38A Antibody

• Catalog number
  5521
• Price
  Please ask
• Size
  0.02 mg, 0.1 mg

• Gene info
  TMEM38A Antibody: TMEM38A and TMEM38B are two recently identified trimeric intracellular cation (TRIC) channel subtypes. TMEM38A is preferentially expressed in excitable tissues such as striated muscle and brain and localizes to the sarcoplasmic reticulum (SR) in muscle tissues. Mice deficient in both TMEM38A and TMEM38B suffer embryonic cardiac failure; the cardiac myocytes display severe dysfunction in SR Ca2+ handling, weakened Ca2+ release, and reduced K+ permeability indicating that the TRIC cation channels are likely to act as counter-ion channels that function in synchronization with Ca2+ release from intracellular stores. Other experiments have shown that TMEM38A and TMEM38B can act with junctophilin proteins to support efficient ryanodine receptor-mediated Ca2+ release in muscle cells.
• Gene names
  TMEM38A Antibody: TRICA, TRIC-A, Trimeric intracellular cation channel type A, Transmembrane protein 38A
• Antibodie s label
  unlabelled serum
• Purity
  TMEM38A Antibody is affinity chromatography purified via peptide column.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Immunoglobulin
  IgG
• Antigen
  TMEM38A antibody was made against a 17 amino acid synthetic peptide from near the carboxy terminus of human TMEM38A.
• Immuno application
  ELISA, Western Blot, immuno fluorescence
• Antibody advice
  TMEM38A antibody can be used for detection of TMEM38A by Western blot at 1 ug/mL. For immunofluorescence start at 20 ug/mL.
• Suspention pH azide
  TMEM38A Antibody is supplied in PBS containing 0.02% sodium azide.
• Keep at
  TMEM38A antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
• Works with
  Human, Mouse, Rat
• Omim nr
  12654711
• Ncbi nr
  AAH01195
• Vial with antibody
  in solution
• Quantity per ml
  1 mg/mL
• NCBI GENE nr
  79041
• GENE symbol
  TMEM38A
• Antigene name
  transmembrane protein 38A
• Source
  Homo sapiens
• Protein nr
  Q9H6F2
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  TMEM38A  
• Gene symbol
  TMEM38A
• Short name
  anti-TMEM38A Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toTMEM38A (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:28462
• Gene
  TMEM38A
• Long gene name
  transmembrane protein 38A
• Synonyms
  • MGC3169
  • TRIC-A
• GenBank acession
  • AK025981
• Locus
  19p13.11
• Discovery year
  2004-12-21
• Entrez gene record
  79041
• Pubmed identfication
  • 17611541
• RefSeq identity
  • NM_024074
• VEGA ID
  OTTHUMG00000182639

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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