anti-TLR9 Antibody [26C593.2]
-
Catalog number
49-862
-
Price
Please ask
-
Size
0.05 mg
-
-
Gene info
The Toll-like receptor (TLR) family in mammal comprises a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and IL-1 receptor motif in the cytoplasmic domain. Like its counterparts in Drosophila, TLRs signal through adaptor molecules. The TLR family is a phylogenetically conserved mediator of innate immunity that is essential for microbial recognition. Ten human homologs of TLRs (TLR1-10) have been described. By using a BLAST search, Hemmi et al., 2000 have identified and subsequently isolated a cDNA coding for TLR9. Gene knockout experiments suggest that TLR9 acts as a receptor for unmethylated CpG dinucleotides in the bacterial DNA. Human and mouse TLR9 share an overall amino-acid identity of 75.5%. TLR9 is highly expressed in spleen.
-
Gene names
TLR9, CD289, CD289 antigen, Scri2a, Toll-like receptor 9
-
Antibodie s label
unlabelled serum
-
Purity
Protein G Column
-
Ab raised in
Mouse
-
Type
Monoclonal
-
Monoclonal
[26C593.2]
-
Immunoglobulin
IgG1,k
-
Antigen
TLR9 monoclonal antibody was made against amino acids 268 - 284 of TLR9 (Human).
-
Immuno application
Western Blot, immuno-histo-chemistry, FLOW
-
Antibody advice
TLR9 antibody can be used in Western Blot starting at 0.5 - 2 ug/mL, immunohistochemistry starting at 5 ug/mL, and immunoprecipitation.
-
Suspention pH azide
PBS, 0.05% BSA, 0.05% sodium azide.
-
Keep at
Store TLR9 antibody at 4 grades C or -20 grades C. As with all antibodies avoid freeze/thaw cycles.
-
Works with
Gibbon, Gorilla, Human, Mouse, Orangutan, Rat
-
Omim nr
20140872
-
Ncbi nr
Q9NR96
-
Vial with antibody
in solution
-
NCBI GENE nr
54106
-
GENE symbol
TLR9
-
Antigene name
toll-like receptor 9
-
Source
Homo sapiens
-
Protein nr
Q9NR96
-
-
-
-
Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
-
Properties
If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
French translation
anticorps
-
Gene target
-
Gene symbol
TLR9
-
Short name
anti-TLR9 Antibody [26C593 2]
-
Technique
Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
-
Alternative name
Antibody toTLR9 (antibody to-) [26C593.2]
-
Alternative technique
antibodies
-
Alternative to gene target
toll-like receptor 9, TLR9 and IDBG-407857 and ENSG00000239732 and 54106, siRNA binding, Extracellular
-
Gene info
-
Identity
-
Gene
-
Long gene name
toll like receptor 9
-
Synonyms gene name
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year
2001-04-27
-
Entrez gene record
-
Pubmed identfication
-
Classification
- Toll like receptors
- My-T-BRC complex
- CD molecules
-
VEGA ID
MeSH Data
-
Name
-
Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Similar products