TLR2 Polyclonal Antibody
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Catalog numberA1075-100
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PricePlease ask
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Size100 µl
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Antibody TargetTLR2
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Target Alternative NameToll-like receptor 2, Toll/interleukin-1 receptor-like protein 4, CD282, TLR2, TIL4
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Antibody TypePolyclonal
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Species ReactivitiesHuman
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Immunogen SequenceKLH conjugated synthetic peptide between 212-242 amino acids from the N-terminal region of human TLR2.
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AccessionO60603
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Gene Id7097
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AppearanceColorless liquid
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FormLiquid
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FormulationPBS with 0.09% (W/V) sodium azide.
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PurificationSaturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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ApplicationWB, IHC-P, FC
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Positive ControlWB, IHC-P, FC
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Application And UsagesWB~~1:1000, IHC-P~~1:10~50, FC~~1:10~5
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DescriptionThe protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB.
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Storage Condition-20°C
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Shipping Conditiongel pack
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Shelf Life12 months
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UsageFor Research Use Only! Not to be used in humans
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HandlingThe antibody solution should be gently mixed before use
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Western Blot VerifiedVerified
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Immunocytochemistry VerifiedNot Verified
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Immunofluorescence VerifiedNot Verified
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Immunoprecipitation VerifiedNot Verified
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ELISA VerifiedNot Verified
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ChIP VerifiedNot Verified
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Dot Blot VerifiedNot Verified
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Flow Cytometry VerifiedVerified
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PropertiesIf you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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GroupPolyclonals and antibodies
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AboutPolyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
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French translationanticorps
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Gene target
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Gene symbolTLR2
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Short nameTLR2 Polyclonal Antibody
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TechniquePolyclonal, Antibody, antibodies against human proteins, antibodies for, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
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IsotypeRabbit IgG
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Alternative nametoll-like receptor 2 polyclonal (antibody to-)
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Alternative techniquepolyclonals, antibodies
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Alternative to gene targettoll-like receptor 2, CD282 and TIL4, TLR2 and IDBG-41789 and ENSG00000137462 and 7097, lipopeptide binding, Cell surfaces, Tlr2 and IDBG-154818 and ENSMUSG00000027995 and 24088, TLR2 and IDBG-629032 and ENSBTAG00000008008 and 281534
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Gene info
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Identity
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Gene
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Long gene nametoll like receptor 2
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Synonyms gene name
- toll-like receptor 2
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Synonyms
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GenBank acession
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Locus
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Discovery year1998-06-25
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Entrez gene record
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Pubmed identfication
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Classification
- Toll like receptors
- CD molecules
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data