Smad7 Antibody

• Catalog number
  3670-100
• Price
  Please ask
• Size
  100 µg

• Antibody Target
  Smad7
• Target Alternative Name
  SMAD7 , MADH7, MADH8 , Smad7; hSMAD7; SMAD family member 7
• Antibody Type
  Polyclonal
• Species Reactivities
  Human, mouse, rat
• Immunogen Sequence
  Synthetic peptide from human Smad 7
• Accession
  AAB81354.1
• Gene Id
  4092
• Appearance
  Colorless liquid
• Form
  Liquid
• Concentration
  0.5 mg/ml
• Formulation
  100 µg (0.5 mg/ml) affinity purified rabbit anti-Smad7 polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.
• Purification
  Affinity purified
• Application
  Western blot
• Application And Usages
  Western blotting (0.5-4 µg/ml). However, the optimal concentrations should be determined individually. Other applications have not been determined. The antibody detects ~46 kDa Smad-7 from samples of human, mouse, and rat origins. Reactivity to other species has not been determined.
• Description
  Smad proteins, the mammalian homologs of the Drosophila Mothers against dpp (Mad), have been implicated as downstream effectors of TGFβ/BMP signaling. Smad1, Smad5, and Smad8 are effectors of BMP2 and BMP4 function while Smad2 and Smad3 are involved in TGF-β and activin-mediated growth modulation. Smad4 has been shown to mediate all of the above activities throμgh interaction with various Smad family members. Smad6 and Smad7 regulate the response to activin/TGFβ signaling by interfering with TGFβ-mediated phosphorylation of other Smad family members.
• Storage Condition
  -20 °C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans.
• Handling
  The antibody solution should be gently mixed before use.
• Western Blot Verified
  Verified
• Immunocytochemistry Verified
  Not Verified
• Immunofluorescence Verified
  Not Verified
• Immunoprecipitation Verified
  Not Verified
• FACS Verified
  Not Verified
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Smad7  
• Gene symbol
  SMAD7
• Short name
  Smad7 Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  SMAD family member 7 (antibody to-)
• Alternative technique
  antibodies
• Alternative to gene target
  SMAD family member 7, CRCS3 and MADH7 and MADH8, SMAD7 and IDBG-3195 and ENSG00000101665 and 4092, transforming growth factor beta receptor, nuclei, Smad7 and IDBG-158890 and ENSMUSG00000025880 and 17131, SMAD7 and IDBG-644653 and ENSBTAG00000012441 and 535916

Gene info

• Identity
  HGNC:6773
• Gene
  SMAD7
• Long gene name
  SMAD family member 7
• Synonyms gene
  • MADH8
  • MADH7
• Synonyms gene name
  • MAD, mothers against decapentaplegic homolog 7 (Drosophila)
  • SMAD, mothers against DPP homolog 7 (Drosophila)
• GenBank acession
  • AF010193
• Locus
  18q21.1
• Discovery year
  1997-08-22
• Entrez gene record
  4092
• Pubmed identfication
  • 9256479
  • 9730599
• RefSeq identity
  • NM_005904
• Classification
  • SMAD family
• VEGA ID
  OTTHUMG00000132655

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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