anti-SIPA1L1 Antibody
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Catalog number5491
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Price:
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Size0.02 mg, 0.1 mg
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Gene infoSIPA1L1 Antibody: Signal-induced proliferation associated-like protein 1 (SIPA1L1) is a member of the SIPA1 family of RapGAPs. SIPA1L1 was initially identified as a binding partner and degradation target of the E6 oncoprotein of high-risk papillomaviruses. Recently, it was discovered that Casein kinase I epsilon (CKIe), a Wnt-regulated kinase that regulates Wnt/b-catenin signaling, also can bind to the carboxy-terminus of SIPA1L1. CKIe phosphorylates SIPA1L1, thereby reducing its stability and alleviating its inhibition of Rap1, a protein required for Wnt8/CKIe-mediated gastrulation during embryogenesis, suggesting SIPA1L1 plays important roles in embryo development as well as control of cell proliferation.
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Gene namesSIPA1L1 Antibody: E6TP1, E6TP1, KIAA0440, Signal-induced proliferation-associated 1-like protein 1, High-risk human papilloma viruses E6 oncoproteins targeted protein 1, SIPA1-like protein 1
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Antibodie s labelunlabelled serum
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PuritySIPA1L1 Antibody is affinity chromatography purified via peptide column.
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Ab raised inRabbit
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TypePolyclonal
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ImmunoglobulinIgG
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AntigenSIPA1L1 antibody was made against a 16 amino acid synthetic peptide from near the amino terminus of human SIPA1L1.
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Immuno applicationELISA, Western Blot, immuno-histo-chemistry, immuno fluorescence
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Antibody adviceSIPA1L1 antibody can be used for detection of SIPA1L1 by Western blot at 0.5 - 1 ug/mL. Antibody can also be used for immunohistochemistry starting at 5 ug/mL. For immunofluorescence start at 20 ug/mL.
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Suspention pH azideSIPA1L1 Antibody is supplied in PBS containing 0.02% sodium azide.
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Keep atSIPA1L1 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Works withHuman, Mouse, Rat
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Omim nr7662126
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Ncbi nrNP_056371
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Vial with antibodyin solution
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Quantity per ml1 mg/mL
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NCBI GENE nr26037
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GENE symbolSIPA1L1
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Antigene namesignal-induced proliferation-associated 1 like 1
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SourceHomo sapiens
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Protein nrO43166
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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PropertiesIf you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolSIPA1L1-AS1, SIPA1L1
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Short nameanti-SIPA1L1 Antibody
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TechniqueAntibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
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Alternative nameAntibody toSIPA1L1 (antibody to-)
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene nameSIPA1L1 antisense RNA 1
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Locus
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Discovery year2021-01-08
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Entrez gene record
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Classification
- Antisense RNAs
Gene info
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Identity
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Gene
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Long gene namesignal induced proliferation associated 1 like 1
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Synonyms gene name
- signal-induced proliferation-associated 1 like 1
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2003-12-11
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- PDZ domain containing
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data