anti-SHISA4 Antibody

• Catalog number
  7277
• Price
  Please ask
• Size
  0.02 mg, 0.1 mg

• Gene info
  SHISA4 Antibody: SHISA4 plays an essential role in the maturation of presomitic mesoderm cells by individual attenuation of both FGF and WNT signaling. The Shisa family of single-transmembrane proteins is characterized by an N-terminal cysteine-rich domain and a proline-rich C-terminal region. Its founding member, Xenopus Shisa, promotes head development by antagonizing Wnt and FGF signaling. Shisa physically interacted with immature forms of the Wnt receptor Frizzled and the FGF receptor within the ER and inhibited their posttranslational maturation and trafficking to the cell surface. Loss of Shisa function sensitized the neuroectoderm to Wnt signaling and suppressed head formation during gastrulation.
• Gene names
  SHISA4 Antibody: TMEM58, C1orf40, TMEM58, UNQ583/PRO1153, Protein shisa-4, Transmembrane protein 58
• Antibodie s label
  unlabelled serum
• Purity
  SHISA4 Antibody is affinity chromatography purified via peptide column.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Immunoglobulin
  IgG
• Spicific to
  SHISA4 antibody is predicted to not cross-react with other SHISA protein family members.
• Antigen
  SHISA4 antibody was made against a 15 amino acid peptide near the center of human SHISA4 .
• Immuno application
  ELISA, Western Blot, immuno-histo-chemistry, immuno fluorescence
• Antibody advice
  SHISA4 Antibody can be used for detection of SHISA4 by Western blot starting at 1 ug/mL.
• Suspention pH azide
  SHISA4 Antibody is supplied in PBS containing 0.02% sodium azide.
• Keep at
  SHISA4 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year.
• Works with
  Human, Mouse
• Omim nr
  269973884
• Ncbi nr
  NP_937792
• KDa
  Predicted: 22 kDa Observed: 24 kDa
• Vial with antibody
  in solution
• Quantity per ml
  1 mg/mL
• NCBI GENE nr
  149345
• GENE symbol
  SHISA4
• Antigene name
  shisa homolog 4 (Xenopus laevis)
• Source
  homo sapiens
• Protein nr
  Q96DD7
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  SHISA4  
• Gene symbol
  SHISA4
• Short name
  anti-SHISA4 Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toSHISA4 (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:27139
• Gene
  SHISA4
• Long gene name
  shisa family member 4
• Synonyms gene
  • C1orf40
  • TMEM58
• Synonyms gene name
  • chromosome 1 open reading frame 40
  • transmembrane protein 58
  • shisa homolog 4 (Xenopus laevis)
• Synonyms
  • hShisa4
• GenBank acession
  • AY358589
• Locus
  1q32.1
• Discovery year
  2004-01-09
• Entrez gene record
  149345
• Pubmed identfication
  • 12975309
• RefSeq identity
  • NM_198149
• Classification
  • Shisa family members
• VEGA ID
  OTTHUMG00000035807

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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