anti-SEC62 Antibody

• Catalog number
  6471
• Price
  Please ask
• Size
  0.02 mg, 0.1 mg

• Gene info
  SEC62 Antibody: SEC62 is an integral membrane protein located in the rough endoplasmic reticulum (ER) and is part of the SEC61-SEC62-SEC63 complex that is the central component of the protein translocation apparatus of the ER membrane. It is speculated that SEC61-SEC62-SEC63 may perform post-translational protein translocation into the ER and might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. Silencing of this gene with RNAi dramatically reduced the migration and invasive potential of numerous tumor cell lines, suggesting that it may be an attractive target for therapy of various tumors.
• Gene names
  SEC62 Antibody: HTP1, TP-1, Dtrp1, TLOC1, Translocation protein SEC62, Translocation protein 1
• Antibodie s label
  unlabelled serum
• Purity
  SEC62 Antibody is affinity chromatography purified via peptide column.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Immunoglobulin
  IgG
• Spicific to
  SEC62 antibody is predicted to not cross-react with other SEC proteins. Multiple isoforms of SEC62 are known to exist.
• Antigen
  SEC62 antibody was made against an 18 amino acid synthetic peptide near the carboxy terminus of human SEC62.
• Immuno application
  ELISA, Western Blot, immuno-histo-chemistry, immuno fluorescence
• Antibody advice
  SEC62 antibody can be used for detection of SEC62 by Western blot at 0.5 - 1 ug/mL. Antibody can also be used for immunohistochemistry starting at 5 ug/mL. For immunofluorescence start at 20 ug/mL.
• Suspention pH azide
  SEC62 Antibody is supplied in PBS containing 0.02% sodium azide.
• Keep at
  SEC62 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
• Works with
  Human, Mouse, Rat
• Omim nr
  4507525
• Ncbi nr
  NP_003253
• Vial with antibody
  in solution
• Quantity per ml
  1 mg/mL
• NCBI GENE nr
  7095
• GENE symbol
  SEC62
• Antigene name
  SEC62 homolog (S. cerevisiae)
• Source
  Homo sapiens
• Protein nr
  Q99442
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  SEC62  
• Gene symbol
  SEC62-AS1, SEC62
• Short name
  anti-SEC62 Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toSEC62 (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:40586
• Gene
  SEC62-AS1
• Long gene name
  SEC62 antisense RNA 1
• Synonyms gene name
  • SEC62 antisense RNA 1 (non-protein coding)
• Locus
  3q26.2
• Discovery year
  2011-07-28
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000158754

Gene info

• Identity
  HGNC:11846
• Gene
  SEC62
• Long gene name
  SEC62 homolog, preprotein translocation factor
• Synonyms gene
  • TLOC1
• Synonyms gene name
  • translocation protein 1
  • SEC62 homolog (S. cerevisiae)
• Synonyms
  • Dtrp1
  • HTP1
• GenBank acession
  • D87127
• Locus
  3q26.2
• Discovery year
  1998-05-05
• Entrez gene record
  7095
• Pubmed identfication
  • 9020021
  • 10799540
  • 22375059
• VEGA ID
  OTTHUMG00000158753

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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