-
Gene info
RBM8A is a protein with a conserved RNA-binding motif. The protein is found predominantly in the nucleus, although it is also present in the cytoplasm. It is preferentially associated with mRNAs produced by splicing, including both nuclear mRNAs and newly exported cytoplasmic mRNAs. It is thought that the protein remains associated with spliced mRNAs as a tag to indicate where introns had been present, thus coupling pre- and post-mRNA splicing events.This gene encodes a protein with a conserved RNA-binding motif. The protein is found predominantly in the nucleus, although it is also present in the cytoplasm. It is preferentially associated with mRNAs produced by splicing, including both nuclear mRNAs and newly exported cytoplasmic mRNAs. It is thought that the protein remains associated with spliced mRNAs as a tag to indicate where introns had been present, thus coupling pre- and post-mRNA splicing events. Previously, it was thought that two genes encode this protein, RBM8A and RBM8B; it is now thought that the RBM8B locus is a pseudogene. Two alternative start codons result in two forms of the protein, and this gene also uses multiple polyadenylation sites.
-
Gene names
RBM8A, TAR, Y14, RBM8, ZNRP, RBM8B, ZRNP1, BOV-1A, BOV-1B, BOV-1C, MDS014, DEL1q21.1, C1DELq21.1
-
Antibodie s label
unlabelled serum
-
Purity
Antibody is purified by protein A chromatography method.
-
Ab raised in
Rabbit
-
Type
Polyclonal
-
Antigen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human RBM8A.
-
Immuno application
ELISA, Western Blot, immuno-histo-chemistry
-
Antibody advice
RBM8A antibody can be used for detection of RBM8A by ELISA at 1:62500. RBM8A antibody can be used for detection of RBM8A by western blot at 1.25 ug/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
-
Suspention pH azide
Antibody is lyophilized in PBS buffer with 2% sucrose. Add 100 μL of distilled water. Final antibody concentration is 1 mg/mL.
-
Keep at
For short periods of storage (days) store at 4 grades C. For longer periods of storage, store RBM8A antibody at -20 grades C. As with any antibody avoid repeat freeze-thaw cycles.
-
Works with
Human, Mouse, Rat, Dog, Zebrafish
-
Omim nr
4826972
-
Ncbi nr
NP_005096
-
KDa
19 kDa
-
Vial with antibody
Lyophilized
-
Quantity per ml
1 mg/ml
-
NCBI GENE nr
9939
-
GENE symbol
RBM8A
-
Antigene name
RNA binding motif protein 8A
-
Source
Homo sapiens
-
Protein nr
Q9Y5S9
-
-
-
-
Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
-
Properties
If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
French translation
anticorps
