RARA polyclonal antibody
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Catalog number6826-50
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PricePlease ask
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Size50 μl
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Antibody TargetRARA
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Target Alternative NameRetinoic acid receptor alpha, Nuclear receptor subfamily 1 group B member 1, NR1B1
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Antibody TypePolyclonal
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Species ReactivitiesHuman.
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Immunogen SequenceHuman RARA (Retinoic Acid Receptor alpha) using two KLH-conjugated synthetic peptides containing sequences from the C-terminal region of the protein.
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AccessionP10276
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Gene Id5914
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AppearanceColorless liquid
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FormLiquid
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FormulationIn PBS with 0.05% (W/V) sodium azide.
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PurificationWhole Anti-Sera
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ApplicationWestern blot, ELISA, ChIP.
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Positive ControlWestern blot: Human embryonic kidney cells, ELISA: peptides, ChIP: NB4 cells.
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Application And UsagesChIP: 4 µg/ChIP, WB: 1:750, ELISA: 1:50.
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DescriptionRARA is a receptor for retinoic acid, a vitamin A metabolite, which directly regulates gene expression in target cells by binding to specific DNA response elements. In the absence of its ligand, this receptor represses transcription through the recruitment of specific corepressors and of HDAC’s, whereas binding of retinoic acid causes the recruitment of coactivators and HAT’s. Translocations involving the RARA gene, often leading to a RARA/PML fusion protein, are a major cause of acute promyelocytic leukemia.
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Storage Condition-20 °C
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Shipping Conditiongel pack
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Shelf Life12 months
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UsageFor Research Use Only! Not to be used in humans.
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HandlingThe antibody solution should be gently mixed before use.
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Western Blot VerifiedVerified
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Immunocytochemistry VerifiedNot Verified
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Immunofluorescence VerifiedNot Verified
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Immunoprecipitation VerifiedNot Verified
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ELISA VerifiedVerified
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ChIP VerifiedVerified
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Dot Blot VerifiedNot Verified
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Flow Cytometry VerifiedNot Verified
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PropertiesIf you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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GroupPolyclonals and antibodies
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AboutPolyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
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French translationanticorps
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Gene target
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Gene symbolRARA-AS1, RARA
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Short nameRARA polyclonal antibody
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TechniquePolyclonal, Antibody, antibodies against human proteins, antibodies for, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
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IsotypeRabbit IgG
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Alternative nameretinoic acid receptor, alpha polyclonal (antibody to-)
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Alternative techniquepolyclonals, antibodies
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Alternative to gene targetretinoic acid receptor, alpha, NR1B1 and RAR, RARA and IDBG-47411 and ENSG00000131759 and 5914, translation repressor activity, nuclei, Rara and IDBG-210842 and ENSMUSG00000037992 and 19401, RARA and IDBG-639652 and ENSBTAG00000012500 and 534280
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Gene info
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Identity
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Gene
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Long gene nameRARA antisense RNA 1
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GenBank acession
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Locus
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Discovery year2014-01-17
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Entrez gene record
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Classification
- Antisense RNAs
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameretinoic acid receptor alpha
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Synonyms gene name
- retinoic acid receptor, alpha
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Synonyms
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GenBank acession
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Locus
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Discovery year1988-06-09
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Entrez gene record
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Pubmed identfication
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Classification
- Retinoic acid receptors
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data