anti-RAB21 Antibody
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Catalog number6927
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PricePlease ask
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Size0.02 mg, 0.1 mg
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Gene infoRAB21 Antibody: RAB21 is a member of a subfamily of small GTP-binding protein genes of the Ras superfamily that plays an important role in intracellular vesicular targeting. In non-polarized Caco-2 cells, RAB21 showed a general endoplasmic reticulum (ER)-like localization, while in polarized cells, RAB21 localized to apical vesicles. RAB21 has been shown to associate with integrin subunits and to be important for receptor entry into cells via RAB5/RAB21 endosomes. The GTPase-activating protein p120RasGAP regulates cell motility by controlling the return of the endocytosed integrins to the plasma membrane by competing with RAB21 for binding to overlapping sites on the a;-tail of endocytosed integrin.
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Gene namesRAB21 Antibody: KIAA0118, Ras-related protein Rab-21
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Antibodie s labelunlabelled serum
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PurityRAB21 Antibody is affinity chromatography purified via peptide column.
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Ab raised inRabbit
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TypePolyclonal
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ImmunoglobulinIgG
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Spicific toThis antibody is predicted to not cross-react with other Ras-related proteins
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AntigenRAB21 antibody was made against a 19 amino acid synthetic peptide near the carboxy terminus of human RAB21.
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Immuno applicationELISA, Western Blot, immuno fluorescence
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Antibody adviceRAB21 antibody can be used for detection of RAB21 by Western blot at 1 ug/mL. For immunofluorescence start at 20 ug/mL.
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Suspention pH azideRAB21 Antibody is supplied in PBS containing 0.02% sodium azide.
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Keep atRAB21 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Works withHuman, Mouse, Rat
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Omim nr7661922
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Ncbi nrNP_055814
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Vial with antibodyin solution
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Quantity per ml1 mg/mL
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NCBI GENE nr23011
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GENE symbolRAB21
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Antigene nameRAB21, member RAS oncogene family
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SourceHomo sapiens
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Protein nrQ9UL25
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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PropertiesIf you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolRAB21
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Short nameanti-RAB21 Antibody
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TechniqueAntibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
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Alternative nameAntibody toRAB21 (antibody to-)
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene nameRAB21, member RAS oncogene family
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Synonyms
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GenBank acession
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Locus
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Discovery year2002-02-19
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Entrez gene record
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Pubmed identfication
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Classification
- RAB, member RAS oncogene GTPases
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data